A4SF07 (SYD_PROVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Aspartate--tRNA ligase
EC=6.1.1.12

Alternative name(s):
Aspartyl-tRNA synthetase
Short name=AspRS

Gene names

Name:	aspS
Ordered Locus Names:	Cvib_1052

Organism

Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]

Taxonomic identifier

290318 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	602 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044_B
Subunit structure	Homodimer By similarity. HAMAP MF_00044_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00044_B.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA aminoacylation for protein translation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW aspartate-tRNA ligase activity Inferred from electronic annotation. Source: EC nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 602	602	Aspartate--tRNA ligase HAMAP MF_00044_B		PRO_1000074713

Sequences

	Sequence		Length	Mass (Da)
	A4SF07 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 4AE6CE2021136C15	FASTA	602	68,115
	10 20 30 40 50 60 MTNAAGSSSA LQNRFRTHYC GSLGPVLQQE KVSLAGWVHR IRDHGGLVFI DLRDHTGICQ 70 80 90 100 110 120 LVIQPEEKEL FEQASHLHAE SVIAIEGSVV LRSPETVNAR LASGAIEVVV SALTVESNAR 130 140 150 160 170 180 PLPFPVADEL PTSEELRLKY RFIDLRREKI HENIIFRSRV SSAIRRYLEE RDFVEIQTPI 190 200 210 220 230 240 LTSSSPEGAR DFLVPSRLHP GKFYALPQAP QQFKQLLMVA GFPRYFQIAP CFRDEDARAD 250 260 270 280 290 300 RSPGEFYQLD MEMAFIEQDD LFEILEGMFR HLVTSMSKKR ITAFPFPRIS YRDVMNRFGT 310 320 330 340 350 360 DKPDLRIPLE IADVTPLFVN SGFKVFAANT KEGCAVKALV LKGRGTESRL FYDKAEKRAK 370 380 390 400 410 420 ELGSAGLAYI QFREEGLKGP IVKFMSEGEI ASMKEQLSLE TGDVVFFAAG KWEAACRIMG 430 440 450 460 470 480 GMRTYFGELF TLDHDELSFC WIVDFPMYEY NEEAGKIDFS HNPFSMPQGE MEALETMDPL 490 500 510 520 530 540 ELLAYQYDIV CNGIELSSGA IRNHRPDIMY RAFEIAGYSK EDVDLRFGHM IEAFKLGAPP 550 560 570 580 590 600 HGGIAPGLDR LVMILRDEQN IREVIAFPMN QQAEDLMMSA PSEVTTAQLR ELHIKLDLPK ED

References

[1]

"Complete sequence of Prosthecochloris vibrioformis DSM 265." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 265.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000607 Genomic DNA. Translation: ABP37066.1.
RefSeq	YP_001130568.1. NC_009337.1.
3D structure databases
ProteinModelPortal	A4SF07.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SF07.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4970977.
GenomeReviews	Gene locus Cvib_1052 in contig CP000607_GR.
KEGG	pvi:Cvib_1052.
PATRIC	21396536. VBIChlPha132153_1109.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0173.
HOGENOM	HBG396032.
OMA	YQLDVEM.
ProtClustDB	PRK00476.
Family and domain databases
HAMAP	MF_00044_B. Asp_tRNA_synth_B. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR004524. Asp-tRNA-synth_IIb_bac/mt. IPR002312. Asp/Asn-tRNA-synth_IIb. IPR004115. GAD_dom. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:3.30.1360.30. GAD_dom. 1 hit. G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K01876.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF5. AspS_bac. 1 hit.
Pfam	PF02938. GAD. 1 hit. PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF55261. SSF55261. 1 hit.
TIGRFAMs	TIGR00459. AspS_bact. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYD_PROVI

Accession

Primary (citable) accession number: A4SF07

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program