Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Argininosuccinate lyase

Gene

argH

Organism
Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.UniRule annotationSAAS annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Argininosuccinate synthase (argG)
  3. Argininosuccinate lyase (argH)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate, the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processAmino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00068; UER00114

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate lyaseUniRule annotationSAAS annotation (EC:4.3.2.1UniRule annotationSAAS annotation)
Short name:
ASALUniRule annotation
Alternative name(s):
ArginosuccinaseUniRule annotation
Gene namesi
Name:argHUniRule annotation
Ordered Locus Names:Cvib_0883Imported
OrganismiChlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))Imported
Taxonomic identifieri290318 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000006700 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi290318.Cvib_0883

Structurei

3D structure databases

ProteinModelPortaliA4SEI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 321Lyase_1InterPro annotationAdd BLAST294
Domaini385 – 452ASL_C2InterPro annotationAdd BLAST68

Sequence similaritiesi

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CH7 Bacteria
COG0165 LUCA
HOGENOMiHOG000242744
KOiK01755
OMAiSIMPHKK
OrthoDBiPOG091H026A

Family and domain databases

CDDicd01359 Argininosuccinate_lyase, 1 hit
Gene3Di1.10.275.10, 2 hits
HAMAPiMF_00006 Arg_succ_lyase, 1 hit
InterProiView protein in InterPro
IPR029419 Arg_succ_lyase_C
IPR009049 Argininosuccinate_lyase
IPR024083 Fumarase/histidase_N
IPR020557 Fumarate_lyase_CS
IPR000362 Fumarate_lyase_fam
IPR022761 Fumarate_lyase_N
IPR008948 L-Aspartase-like
PANTHERiPTHR43814 PTHR43814, 1 hit
PfamiView protein in Pfam
PF14698 ASL_C2, 1 hit
PF00206 Lyase_1, 1 hit
PRINTSiPR00149 FUMRATELYASE
SUPFAMiSSF48557 SSF48557, 1 hit
TIGRFAMsiTIGR00838 argH, 1 hit
PROSITEiView protein in PROSITE
PS00163 FUMARATE_LYASES, 1 hit

Sequencei

Sequence statusi: Complete.

A4SEI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAHDSPFPS IQPPAAMSNK KELLWASRFN EPFDEGALKF SSSVHVDGKL
60 70 80 90 100
FREDIQGSIA HATMLGEEGI ITKEDARQIT AGLSEIEKEI ESGTLVPQWE
110 120 130 140 150
DEDIHTVIEN RLKEKIGAVA GKLHSGRSRN DQVATDTRLY MRAKVNELHT
160 170 180 190 200
SLTGLMETLV ERADTYQSSI IFGYTHLQRA QPISAGHYYL AYFNMFWRDR
210 220 230 240 250
QRLSDLMQRV NISPLGAAAF AGSTLPLNAE RSAELLGFNS MFSNSIDAVS
260 270 280 290 300
DRDILIEFIS ACSIIMMHLS RFCEDIILWS SYEFGYLEIS DAFSTGSSIM
310 320 330 340 350
PQKKNADIAE LIRGKTGRVY GDLMAMLTIM KGLPLSYNRD MQEDKPPLFD
360 370 380 390 400
SAETAISSVT LFNRMLQHTR LKEDRLKELT AKDLSLATEI AEYLVKKDIP
410 420 430 440 450
FRDAHRITGR IVSWSIEHAT PLPDILLDTY RGFSEVFDEG IFKALTPEAS
460 470
INSKKSHGSC SFESVERQIE EARELLG
Length:477
Mass (Da):53,652
Last modified:May 15, 2007 - v1
Checksum:iE0AD5A954FCC323D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000607 Genomic DNA Translation: ABP36898.1

Genome annotation databases

EnsemblBacteriaiABP36898; ABP36898; Cvib_0883
KEGGipvi:Cvib_0883

Similar proteinsi

Entry informationi

Entry nameiA4SEI9_CHLPM
AccessioniPrimary (citable) accession number: A4SEI9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health