A4SEI5 (ARGB_PROVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Cvib_0879

Organism

Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]

Taxonomic identifier

290318 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Acetylglutamate kinase HAMAP MF_00082_B		PRO_0000335656
Regions
	Region	77 – 78	2	Substrate binding By similarity
Sites
	Binding site	99	1	Substrate By similarity
	Binding site	193	1	Substrate By similarity
	Site	42	1	Transition state stabilizer By similarity
	Site	252	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4SEI5 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: B52CF07B00D7237B	FASTA	302	32,006
	10 20 30 40 50 60 MDHQACNDTT PARKAPQAAI GQVLIEALPY IRKFEGKTFV IKYGGSAMKD ECLKNSFAQN 70 80 90 100 110 120 VTLLRKVGIN VVLVHGGGDA ITKTAEKMGI KSTFVHGKRV TDSDMITIVQ MTLAGKVNQD 130 140 150 160 170 180 IVRLISEHGG KAVGVSGLDA DTIQAVPCHN AETLGLVGEV AAINTAYIDL LCNAGLIPVI 190 200 210 220 230 240 APIGFDDEGH VYNINADDAA SSIAIALKAE KLIYVSDVAG IQAHDAILRT ISKTQAADFI 250 260 270 280 290 300 EQHVITGGMI PKVISAFQTL DGGVGKIHLI DGKCIHSILL EIFTHEGVGT QFIAEQGNDD NQ

References

[1]

"Complete sequence of Prosthecochloris vibrioformis DSM 265." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 265.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000607 Genomic DNA. Translation: ABP36894.1.
RefSeq	YP_001130396.1. NC_009337.1.
3D structure databases
ProteinModelPortal	A4SEI5.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SEI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4970970.
GenomeReviews	Gene locus Cvib_0879 in contig CP000607_GR.
KEGG	pvi:Cvib_0879.
PATRIC	21396164. VBIChlPha132153_0928.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0548.
HOGENOM	HBG497643.
OMA	GGNAMID.
PhylomeDB	A4SEI5.
ProtClustDB	PRK00942.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_PROVI

Accession

Primary (citable) accession number: A4SEI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program