A4SE12 (A4SE12_PROVI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Ordered Locus Names:

Cvib_0706

Organism

Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]

Taxonomic identifier

290318 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862 EMBL ABP36721.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4SE12 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 4C1F16CC1FE69380	FASTA	289	31,767
	10 20 30 40 50 60 MLVKEILNTA HKPVFSFEFF PPKKDADWET LFETITALSP LNPSYVSVTY GAGGSTRTRT 70 80 90 100 110 120 HDLVTRIQKE TGLSVVSHLT CIASTSGETG EILENYQSHG INNVLALRGD KPTGTESIAD 130 140 150 160 170 180 AVKDFPHAID LVRFIKNNHP DIGVGVAGFP EGHPETPNRL QEIEYLKAKV DAGADYIVTQ 190 200 210 220 230 240 LFFDNRDYFD FVDRCRLAGI SVPIIPGIMP VTSTKGMTRM SELALGARIP APLLKKVLGA 250 260 270 280 ENDAQVASIG IEWATNQVQE LIDNQIRGIH FYTLNMATAT LEIFQNLHS

References

[1]

"Complete sequence of Prosthecochloris vibrioformis DSM 265." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 265.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000607 Genomic DNA. Translation: ABP36721.1.
RefSeq	YP_001130223.1. NC_009337.1.
3D structure databases
ProteinModelPortal	A4SE12.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SE12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4970184.
GenomeReviews	Gene locus Cvib_0706 in contig CP000607_GR.
KEGG	pvi:Cvib_0706.
PATRIC	21395788. VBIChlPha132153_0742.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0685.
HOGENOM	HBG649727.
OMA	ITQMFFD.
PhylomeDB	A4SE12.
ProtClustDB	CLSK637732.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4SE12_PROVI

Accession

Primary (citable) accession number: A4SE12

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)