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A4SDH0

- A4SDH0_PROVI

UniProt

A4SDH0 - A4SDH0_PROVI

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Cvib_0507

Organism
Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265))
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (15 May 2007)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei146 – 1461SubstrateUniRule annotation
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganeseUniRule annotation
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481SubstrateUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation
    Metal bindingi553 – 5531Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciCPHA290318:GHNQ-518-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Cvib_0507Imported
    OrganismiProsthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265))Imported
    Taxonomic identifieri290318 [NCBI]
    Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
    ProteomesiUP000006700: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi290318.Cvib_0507.

    Structurei

    3D structure databases

    ProteinModelPortaliA4SDH0.
    SMRiA4SDH0. Positions 7-741.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 1408Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4SDH0-1 [UniParc]FASTAAdd to Basket

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    MAKNATIIYT KIDEAPALAT YSLLPVIQAF VKGTGIGVET RDISLAGRII    50
    ANFPENLTEE QKIPDYLAEL GELALKPEAN IIKLPNISAS IPQLQAAIKE 100
    LQSQGYKIPD YPESPSTDAE KALQARFAKV LGSAVNPVLR EGNSDRRAPL 150
    SVKKYAQNNP HRMAAWSADS KSSIASMASG DFYGSEKSVT IAAPTTVRIE 200
    FVGAEGSVTV LKDKTSLLQD EVIDTAVMNV RSLRSFFEAQ IDAAKKNGTL 250
    LSLHLKATMM KVSDPIMFGH AVSVFYRDVF EKHAAVIKEL GVNVRNGLGD 300
    LYAKIQNLPD AQRSEIEADI QAVYPTRPAL AMVDSDKGIT NLHVPNDIIV 350
    DASMPVVIRD GGKMWGPDGQ LHDTTAMIPD RCYATMYQAM VEDCKKNGAF 400
    DPATIGTVPN VGLMAQKAEE YGSHDKTFTA PAEGFIRVVD AAGTVLMEQA 450
    VETGDIFRMC QAKDAPIRDW VKLAVSRARA TGAPAIFWLD SSRAHDAQLI 500
    EKVGTYLKEH DTAGLDIRIM NPVEAMQFSL GRLRAGQDTI SVTGNVLRDY 550
    LTDLFPIIEL GTSAKMLSVV PLMNGGGLFE TGAGGSAPKH VQQFEKEGYL 600
    RWDSLGEFSA LAASFEYLAS AFSNEKAAVL AETLDQAIGK FLDNRKSPAR 650
    KVGQIDNRGS HFYLALYWAE ALAAQSGDGE LKSRFADVAA KLAAAETAIN 700
    EELIAAQGKP VAMGGYYHVD EALVSAAMRP SATFNAIIDT L 741
    Length:741
    Mass (Da):80,016
    Last modified:May 15, 2007 - v1
    Checksum:i733144D98B33B164
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000607 Genomic DNA. Translation: ABP36529.1.
    RefSeqiWP_011889757.1. NC_009337.1.
    YP_001130031.1. NC_009337.1.

    Genome annotation databases

    EnsemblBacteriaiABP36529; ABP36529; Cvib_0507.
    GeneIDi4971192.
    KEGGipvi:Cvib_0507.
    PATRICi21395366. VBIChlPha132153_0535.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000607 Genomic DNA. Translation: ABP36529.1 .
    RefSeqi WP_011889757.1. NC_009337.1.
    YP_001130031.1. NC_009337.1.

    3D structure databases

    ProteinModelPortali A4SDH0.
    SMRi A4SDH0. Positions 7-741.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290318.Cvib_0507.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP36529 ; ABP36529 ; Cvib_0507 .
    GeneIDi 4971192.
    KEGGi pvi:Cvib_0507.
    PATRICi 21395366. VBIChlPha132153_0535.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci CPHA290318:GHNQ-518-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Prosthecochloris vibrioformis DSM 265."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 265Imported.

    Entry informationi

    Entry nameiA4SDH0_PROVI
    AccessioniPrimary (citable) accession number: A4SDH0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 15, 2007
    Last sequence update: May 15, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3