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A4SDF6 (A4SDF6_PROVI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Cvib_0493
OrganismProsthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]
Taxonomic identifier290318 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405 RuleBase RU003781

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region15 – 206Substrate binding By similarity HAMAP MF_01405
Region84 – 852Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding501Magnesium or manganese By similarity HAMAP MF_01405
Metal binding841Magnesium or manganese By similarity HAMAP MF_01405
Binding site1791Substrate By similarity HAMAP MF_01405
Binding site1991Substrate By similarity HAMAP MF_01405
Binding site2051Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
A4SDF6 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: FA03204361A31CBF

FASTA22023,403
        10         20         30         40         50         60 
MTPISRTPLT IILATANPDK VRELRPLLEG IDPCFSVISL AEAGIAVDIE ETETTLEGNA 

        70         80         90        100        110        120 
MLKANAIFNL LNGRFPAMIA FADDTGLEVN ALGGAPGVYS ARYAPVANGE KPTYRDNVTH 

       130        140        150        160        170        180 
LLNEMEGEKD RSARFRTVIA LKGIVEGKNG TTGIEETIEG LVEGTLTTEA DGSGGFGYDP 

       190        200        210        220 
IFMVTAAGKT YGRMSGTEKN SLSHRALATK KAIAFLHTIL

« Hide

References

[1]"Complete sequence of Prosthecochloris vibrioformis DSM 265."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 265.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000607 Genomic DNA. Translation: ABP36515.1.
RefSeqYP_001130017.1. NC_009337.1.

3D structure databases

ProteinModelPortalA4SDF6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4SDF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4969729.
GenomeReviewsGene locus Cvib_0493 in contig CP000607_GR.
KEGGpvi:Cvib_0493.
PATRIC21395338. VBIChlPha132153_0521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0127.
HOGENOMHBG697237.
OMARGIAFSK.
ProtClustDBPRK14826.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4SDF6_PROVI
AccessionPrimary (citable) accession number: A4SDF6
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info