A4SD83 (SURE_PROVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Cvib_0420

Organism

Prosthecochloris vibrioformis (strain DSM 265) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 265)) (Chlorobium phaeovibrioides (strain DSM 265)) [Complete proteome] [HAMAP]

Taxonomic identifier

290318 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 259	259	5'-nucleotidase surE HAMAP MF_00060		PRO_1000075036
Sites
	Metal binding	15	1	Divalent metal cation By similarity
	Metal binding	16	1	Divalent metal cation By similarity
	Metal binding	46	1	Divalent metal cation By similarity
	Metal binding	102	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4SD83 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: AE8822325501D055	FASTA	259	28,590
	10 20 30 40 50 60 MTKQDRRPEI LVCNDDGIEG EGIHVLAASM KKLGNVTVVA PAEPHSGMSH AMTLGVPLRI 70 80 90 100 110 120 KEFRRNNRFF GHTVSGTPVD CIKVALSHIM PVKPDLIVSG INYGSNTATS TIYSGTVAAA 130 140 150 160 170 180 LEGAIQGVTS IAFSLTTYEH ADFTYAGKFA RKLARKVLQK GLPADTILSA NIPNVPESDI 190 200 210 220 230 240 AGVVITRQGR SRWSEDAIER NDMYGNPYYW LNGTLRLQDS EMDKDEYAVR RNFVTITPLS 250 FDLTNRDFLG TLEQWKLQQ

References

[1]

"Complete sequence of Prosthecochloris vibrioformis DSM 265." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Schuster S.C., Bryant D.A., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 265.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000607 Genomic DNA. Translation: ABP36442.1.
RefSeq	YP_001129944.1. NC_009337.1.
3D structure databases
ProteinModelPortal	A4SD83.
ModBase	Search...
Protein-protein interaction databases
STRING	A4SD83.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4969673.
GenomeReviews	Gene locus Cvib_0420 in contig CP000607_GR.
KEGG	pvi:Cvib_0420.
PATRIC	21395186. VBIChlPha132153_0446.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	SINVIYS.
PhylomeDB	A4SD83.
ProtClustDB	PRK13932.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_PROVI

Accession

Primary (citable) accession number: A4SD83

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 15, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program