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Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

OSTLU_29304

Organism
Ostreococcus lucimarinus (strain CCE9901)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (OSTLU_29304), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (OSTLU_43363)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
ORF Names:OSTLU_29304Imported
OrganismiOstreococcus lucimarinus (strain CCE9901)Imported
Taxonomic identifieri436017 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaprasinophytesMamiellophyceaeMamiellalesBathycoccaceaeOstreococcus
Proteomesi
  • UP000001568 Componenti: Chromosome 20

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiA4SAL7

Interactioni

Protein-protein interaction databases

STRINGi436017.A4SAL7

Structurei

3D structure databases

ProteinModelPortaliA4SAL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 446FAD_binding_2InterPro annotationAdd BLAST396
Domaini501 – 633Succ_DH_flav_CInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG2403 Eukaryota
COG1053 LUCA
HOGENOMiHOG000160475
KOiK00234
OMAiGDSPWEH

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

A4SAL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRACERGCVA ARNALTTSAS GSGSGSGSGR SIATAASSST SSYEIIDHEY
60 70 80 90 100
DALVVGAGGA GLRAAIGLGE HGFKTACVTK LFPTRSHTVA AQGGINAALG
110 120 130 140 150
NMTEDDWRWH AYDTVKGADW LGDQDAIQYM CREAPKAVIE LEKYGMPFSR
160 170 180 190 200
TDEGKIYQRA FGGQSLDYGK GGQAYRCAAA ADRTGHAMLH TLYGAALKHD
210 220 230 240 250
VQFFVEYFAL DLIMDKGECV GIMALCLEDG TLHRFRSHQT ILATGGYGRA
260 270 280 290 300
YFSATSAHTC TGDGNAMVAR AGLPLQDQEF VQFHPTGIYG AGCLITEGSR
310 320 330 340 350
GEGGILRNSE GERFMERYAP SAKDLASRDV VSRSMTLEIR EGRGVGKEKD
360 370 380 390 400
HIYLHLNHLP PELLAERLPG ISETAAIFAG VDVTKEPIPV IPTVHYNMGG
410 420 430 440 450
IPTNYKGEVV APKNGDPDAI VPGLLAAGEA ACASVHGANR LGANSLLDIV
460 470 480 490 500
VFGRACANTV ADKLKRGAPH REIASDAGSN AIERLDKIRN SKGSAPTAML
510 520 530 540 550
RKTMQKVMQE DAAVFRTQET LANGCKRIDD VAAQLDNLKL TDRSLVWNTD
560 570 580 590 600
LVEALELHNL MPNAQTTMHS AEQRKESRGA HAREDFPDRL DDVWMKHTLA
610 620 630
YVENGKVKID YRPNHHYTLD AEMDVIPPKA RVY
Length:633
Mass (Da):68,342
Last modified:May 15, 2007 - v1
Checksum:i1662B8CC27D3308D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000600 Genomic DNA Translation: ABP00770.1
RefSeqiXP_001422453.1, XM_001422416.1

Genome annotation databases

EnsemblPlantsiABP00770; ABP00770; OSTLU_29304
GeneIDi5006691
GrameneiABP00770; ABP00770; OSTLU_29304
KEGGiolu:OSTLU_29304

Similar proteinsi

Entry informationi

Entry nameiA4SAL7_OSTLU
AccessioniPrimary (citable) accession number: A4SAL7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health