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A4RYV6 (A4RYV6_OSTLU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA topoisomerase RuleBase RU000518
EC=5.99.1.2 RuleBase RU000518
Gene names
ORF Names:OSTLU_41359 EMBL ABO96753.1
OrganismOstreococcus lucimarinus (strain CCE9901) [Complete proteome]
Taxonomic identifier436017 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Chlorophyta › Mamiellophyceae › Mamiellales › Ostreococcus

Protein attributes

Sequence length840 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP-independent breakage of single-stranded DNA, followed by passage and rejoining. RuleBase RU000518

Sequence similarities

Belongs to the prokaryotic type I/III topoisomerase family. RuleBase RU004206

Ontologies

Keywords
   LigandDNA-binding RuleBase RU000518
   Molecular functionIsomerase
Topoisomerase RuleBase RU000518
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processDNA topological change

Inferred from electronic annotation. Source: InterPro

   Cellular componentchromosome

Inferred from electronic annotation. Source: InterPro

   Molecular functionDNA topoisomerase type I activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue8401 EMBL ABO96753.1

Sequences

Sequence LengthMass (Da)Tools
A4RYV6 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 1F23971DE9A057A7

FASTA84091,445
        10         20         30         40         50         60 
MWTARARAGG VRRLVASVGA RATRGIAWGG REGGWGETTK TAATARAVAS GATTTTTTTT 

        70         80         90        100        110        120 
TTTTNGKRTL MIVESPAKAK TIEKYLGANA KVLASYGHVR DLVNKQGSVR PEESFAMTWT 

       130        140        150        160        170        180 
STSRQKAAMR DITEALKKTD VLLLATDPDR EGEAISWHLL EVLREKKLLR DDLDVKRVTF 

       190        200        210        220        230        240 
GEITKTAVLD AVGSPRDINV PMVDAYMARR ALDYLFGFTL SGLLWRKLPS SVSLSAGRVQ 

       250        260        270        280        290        300 
SVALRLVCER EEEVEAFVSE PYWTVKASLS SKDGSTFDAA LTHVDGAKLG KFTIASNDEA 

       310        320        330        340        350        360 
EAYAKRVREC DTLRVVEVKH SEAKRTSGPP FTTSTMQQEA NKQLGFGASR TMSAAQRLYE 

       370        380        390        400        410        420 
GAGTGEGLIT YMRTDGTYVA PHAIESLRTT AGELFGDEYV PESPRYFKKK QKNAQEAHEA 

       430        440        450        460        470        480 
IRPTKAGRLP AQVARQIGPG SDEARLYALI WARTMASQMS PALTDRIAAE IASAENDLKL 

       490        500        510        520        530        540 
KANGHRLKFP GFLAAYRTSR PEAAPPSDDA WLPILGEGEG LSVKTDGESL GCEATEHKTS 

       550        560        570        580        590        600 
PPPRYTDGSI VKALEERGIG RPSTYAPILK VLAQREYVAK QGAALVPTTR GRLVSAFLTN 

       610        620        630        640        650        660 
YFETYVDYGF TADLEHKLDD ITSEQVQWKP LLEEWWTPFR DKISSLSELR VSEVIDALDE 

       670        680        690        700        710        720 
KLGQHLFGEA TDSDDVVSEA RRCPSCKIGR LGLKPSKAGG FIGCSRYPEC GFTHPLHPIR 

       730        740        750        760        770        780 
GAIVSDTDDP DFVATVEDPD AVMYPKVLGV DPATGKEISL RLGPYGPYLQ LGDGKKAKKP 

       790        800        810        820        830        840 
KKPPAPRRVG VANIGKDVNK ITLAEAIGMF EYPKVLGVHP VTQAPVSLNI GPFGWYVASE

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000586 Genomic DNA. Translation: ABO96753.1.
RefSeqXP_001418460.1. XM_001418423.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4RYV6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5002409.
KEGGolu:OSTLU_41359.

Phylogenomic databases

HOGENOMHBG512935.
OMAQELDETC.
PhylomeDBA4RYV6.

Family and domain databases

InterProIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR023406. Topo_IA_AS.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd.
IPR013498. Topo_IA_Znf.
IPR005733. TopoI_bac-type.
IPR006171. Toprim_domain.
[Graphical view]
Gene3DG3DSA:1.10.460.10. Topo_IA_cen_sub1. 2 hits.
G3DSA:2.70.20.10. Topo_IA_cen_sub2. 2 hits.
KOK03168.
PANTHERPTHR11390. Topo_IA. 1 hit.
PfamPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
PF01396. zf-C4_Topoisom. 1 hit.
[Graphical view]
PRINTSPR00417. PRTPISMRASEI.
SMARTSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMSSF56712. Topo_IA_core. 1 hit.
TIGRFAMsTIGR01051. TopA_bact. 1 hit.
PROSITEPS00396. TOPOISOMERASE_I_PROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4RYV6_OSTLU
AccessionPrimary (citable) accession number: A4RYV6
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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