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Protein

Mannose-6-phosphate isomerase

Gene

OSTLU_3605

Organism
Ostreococcus lucimarinus (strain CCE9901)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-mannose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. mannose-6-phosphate isomerase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. GDP-mannose biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Ligandi

ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Mannose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.8UniRule annotation)
Gene namesi
ORF Names:OSTLU_3605Imported
OrganismiOstreococcus lucimarinus (strain CCE9901)Imported
Taxonomic identifieri436017 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaprasinophytesMamiellophyceaeMamiellalesBathycoccaceaeOstreococcus
ProteomesiUP000001568: Chromosome 2

Interactioni

Protein-protein interaction databases

STRINGi436017.A4RTK3.

Family & Domainsi

Sequence similaritiesi

Belongs to the mannose-6-phosphate isomerase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1482.
HOGENOMiHOG000198011.
KOiK01809.
OMAiDSEPHAY.

Family and domain databases

Gene3Di2.60.120.10. 3 hits.
InterProiIPR001250. Man6P_Isoase-1.
IPR016305. Mannose-6-P_Isomerase.
IPR018050. Pmannose_isomerase-type1_CS.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PANTHERiPTHR10309. PTHR10309. 1 hit.
PfamiPF01238. PMI_typeI. 1 hit.
[Graphical view]
PIRSFiPIRSF001480. Mannose-6-phosphate_isomerase. 1 hit.
PRINTSiPR00714. MAN6PISMRASE.
SUPFAMiSSF51182. SSF51182. 1 hit.
TIGRFAMsiTIGR00218. manA. 1 hit.
PROSITEiPS00965. PMI_I_1. 1 hit.
PS00966. PMI_I_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A4RTK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRELRVKHQN YAWGARGSSA VRALALANAQ RHDDARPEDF DDSTPFAELW
60 70 80 90 100
CGTHASGMSD VVGEDGARTP LIEHVKSAAN ATLGERAVAR FGDDVPFLMK
110 120 130 140 150
MLSVARALSV QAHPDKALAV KLHESNPEAY KDDNHKPEMA LCVSETFEAM
160 170 180 190 200
SGFANADAVL TATRRHEEFG RVIGDDDAIE ALRKAVESGQ SNESAALRDA
210 220 230 240 250
FKRVFTALMT AEKGKVETEL RAMEARVRDE GTTATSSSSV ESLFLRLCEQ
260 270 280 290 300
YPGDVGAFCA FVLNYVTLRP GEAIYMAANE PHAYLSGDCV EVMATSDNVV
310 320 330 340 350
RAGLTPKFRD VQVLCDMLTY KLGAPEILTG DVVDACTRRY VPPFDEFLLD
360 370 380 390 400
VVTVSRGTAY GVVAKSGPSV WIVHRGSCAF ASAKDSKTFA AEPGAVFFVD

ADEECGV
Length:407
Mass (Da):44,049
Last modified:May 15, 2007 - v1
Checksum:iCA2D45084CC87541
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei407 – 4071Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000582 Genomic DNA. Translation: ABO94347.1.
RefSeqiXP_001416055.1. XM_001416018.1.

Genome annotation databases

EnsemblPlantsiABO94347; ABO94347; OSTLU_3605.
GeneIDi5000386.
KEGGiolu:OSTLU_3605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000582 Genomic DNA. Translation: ABO94347.1.
RefSeqiXP_001416055.1. XM_001416018.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi436017.A4RTK3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiABO94347; ABO94347; OSTLU_3605.
GeneIDi5000386.
KEGGiolu:OSTLU_3605.

Phylogenomic databases

eggNOGiCOG1482.
HOGENOMiHOG000198011.
KOiK01809.
OMAiDSEPHAY.

Family and domain databases

Gene3Di2.60.120.10. 3 hits.
InterProiIPR001250. Man6P_Isoase-1.
IPR016305. Mannose-6-P_Isomerase.
IPR018050. Pmannose_isomerase-type1_CS.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PANTHERiPTHR10309. PTHR10309. 1 hit.
PfamiPF01238. PMI_typeI. 1 hit.
[Graphical view]
PIRSFiPIRSF001480. Mannose-6-phosphate_isomerase. 1 hit.
PRINTSiPR00714. MAN6PISMRASE.
SUPFAMiSSF51182. SSF51182. 1 hit.
TIGRFAMsiTIGR00218. manA. 1 hit.
PROSITEiPS00965. PMI_I_1. 1 hit.
PS00966. PMI_I_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCE9901Imported.

Entry informationi

Entry nameiA4RTK3_OSTLU
AccessioniPrimary (citable) accession number: A4RTK3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: February 4, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.