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A4RPY8 (CBPYA_MAGO7) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length552 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate By similarity.

Catalytic activity

Release of a C-terminal amino acid with broad specificity.

Subcellular location

Vacuole By similarity.

Sequence similarities

Belongs to the peptidase S10 family.

Ontologies

Keywords
   Cellular componentVacuole
   DomainSignal
   Molecular functionCarboxypeptidase
Hydrolase
Protease
   PTMDisulfide bond
Glycoprotein
Zymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmycelium development

Inferred from expression pattern PubMed 17156450. Source: PAMGO_MGG

phytochelatin biosynthetic process

Inferred from electronic annotation. Source: EnsemblFungi

proteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentfungal-type vacuole

Inferred from electronic annotation. Source: EnsemblFungi

   Molecular_functionserine-type carboxypeptidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Propeptide19 – 133115 By similarity
PRO_0000407453
Chain134 – 552419Carboxypeptidase Y homolog A
PRO_0000407454

Sites

Active site2741 By similarity
Active site4661 By similarity
Active site5271 By similarity

Amino acid modifications

Glycosylation2181N-linked (GlcNAc...) Potential
Glycosylation5161N-linked (GlcNAc...) Potential
Disulfide bond187 ↔ 427 By similarity
Disulfide bond321 ↔ 335 By similarity
Disulfide bond345 ↔ 368 By similarity
Disulfide bond352 ↔ 361 By similarity
Disulfide bond390 ↔ 397 By similarity

Sequences

Sequence LengthMass (Da)Tools
A4RPY8 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: B0F1815B4BD601B5

FASTA55261,593
        10         20         30         40         50         60 
MRIATSTLLV GAASAAFAPQ DGTQRVLNGF DSIKSAAHSI QKPLQTFEEA MASMTSEAKA 

        70         80         90        100        110        120 
NWDHLKLLVP DAEEQAKTFF PKKPKPASRK PDSAWDHIVK GADIQAMWVE GATPEETHRK 

       130        140        150        160        170        180 
IDGKLDNYNL RARSVDPSKL GVDTVKQYSG YLDDEANDKH LFYWFFESRN DPKNDPVVLW 

       190        200        210        220        230        240 
LNGGPGCSSL TGLLFELGPG AINAKIEIVH NPYAWNNNAS VIFLDQPVNV GYSYSGGSVS 

       250        260        270        280        290        300 
NTVAAGKDIY ALLTLFFHQF PEYAKQDFHI AGESYAGHYI PVFASEILSH KKRNINLKSV 

       310        320        330        340        350        360 
LIGNGLTDGL TQYEYYRPMA CGEGGWKAVL SESECQAMDN ALPRCQSMIQ NCYDSGSVWS 

       370        380        390        400        410        420 
CVPASIYCNN AMIGPYQRTG RNVYDIRGPC KDSGNLCYPE LGYISEYLNR REVMEALGAE 

       430        440        450        460        470        480 
VSSYDSCNFD INRNFLFQGD WMQPYHRLVP ELLNQIPVLI YAGDADFICN WLGNQGWTEA 

       490        500        510        520        530        540 
LEWKGKKDYN RADYSPLTLA SAHDVKPYGK VKSSGNFTFM KIFEAGHMVP YDQAEPSVDF 

       550 
VNRWLAGEWF AA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM001231 Genomic DNA. Translation: EHA57949.1.
RefSeqXP_003710561.1. XM_003710513.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING148305.A4RPY8.

Protein family/group databases

MEROPSS10.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiMGG_05663T0; MGG_05663T0; MGG_05663.
GeneID2676004.
KEGGmgr:MGG_05663.

Phylogenomic databases

eggNOGCOG2939.
KOK13289.
OrthoDBEOG7XDBR1.

Family and domain databases

InterProIPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERPTHR11802. PTHR11802. 1 hit.
PfamPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSPR00724. CRBOXYPTASEC.
PROSITEPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCBPYA_MAGO7
AccessionPrimary (citable) accession number: A4RPY8
Secondary accession number(s): G4MP00
Entry history
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: May 15, 2007
Last modified: February 19, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries