A4RDD7 (EIF3I_MAGO7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 3 subunit I
Short name=eIF3i

Alternative name(s):
Eukaryotic translation initiation factor 3 39 kDa subunit homolog
Short name=eIF-3 39 kDa subunit homolog

Gene names

Name:	TIF34
ORF Names:	MGG_01013

Organism

Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) [Complete proteome]

Taxonomic identifier

242507 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Sordariomycetidae › Magnaporthales › Magnaporthaceae › Magnaporthe › Magnaporthe oryzae

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03008
Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the eIF-3 subunit I family. Contains 5 WD repeats.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Domain	Repeat WD repeat
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mycelium development Inferred from expression pattern PubMed 17156450. Source: PAMGO_MGG
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Eukaryotic translation initiation factor 3 subunit I HAMAP-Rule MF_03008		PRO_0000365369
Regions
	Repeat	8 – 49	42	WD 1 HAMAP-Rule MF_03008
	Repeat	50 – 91	42	WD 2 HAMAP-Rule MF_03008
	Repeat	145 – 184	40	WD 3 HAMAP-Rule MF_03008
	Repeat	189 – 228	40	WD 4 HAMAP-Rule MF_03008
	Repeat	286 – 325	40	WD 5 HAMAP-Rule MF_03008

Sequences

	Sequence		Length	Mass (Da)
	A4RDD7 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 56473F3C302277EB	FASTA	341	38,192
	10 20 30 40 50 60 MRPILLSGHE RALTQVKFNP DGDLIFSVAK DQHICVWFAH NGERLGTYHG HQGAIWTVDC 70 80 90 100 110 120 DPTSTIIATG SADNTIKLWE IKTGRCLHTW EFPTAVKRVE FSPDGTRLLG VTEKRMGHLG 130 140 150 160 170 180 TIVVLDVKLD VDAEQNPERA MTIVCDESKA TVAGWSYLAK YIIAGHEDGS VSQYDAKNGD 190 200 210 220 230 240 QLHSVQIHDM GSEIRDLQWS QDRTYFITAS KDKTAKLVTA RDLEVLKTYP ADTPLNSAVI 250 260 270 280 290 300 TPKKDYVILG GGQAAMDVTT TSARQGKFEA RFYHKIFEDE IGRVRGHFGP LNYVAAEPNG 310 320 330 340 KGYASGGEDG YVRVHQFDKG YFDFMYEVER ERKNKMEQAQ Q

References

[1]

"The genome sequence of the rice blast fungus Magnaporthe grisea." Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K., Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D., Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S., Soanes D.M. , Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W. Nature 434:980-986(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 70-15 / ATCC MYA-4617 / FGSC 8958.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM001235 Genomic DNA. Translation: EHA48347.1.
RefSeq	XP_003717931.1. XM_003717883.1.
3D structure databases
ProteinModelPortal	A4RDD7.
ModBase	Search...
Protein-protein interaction databases
STRING	148305.A4RDD7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	MGG_01013T0; MGG_01013T0; MGG_01013.
GeneID	2674740.
KEGG	mgr:MGG_01013.
Phylogenomic databases
eggNOG	COG2319.
KO	K03246.
OrthoDB	EOG44QX8Q.
Family and domain databases
Gene3D	2.130.10.10. 1 hit.
HAMAP	MF_03008. eIF3i.
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
Pfam	PF00400. WD40. 3 hits. [Graphical view]
SMART	SM00320. WD40. 6 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EIF3I_MAGO7

Accession

Primary (citable) accession number: A4RDD7
Secondary accession number(s): G4NCV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	May 15, 2007
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program