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A4QYQ5 (DAPB_MAGO7) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:DAPB
ORF Names:MGG_07745
OrganismMagnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) [Complete proteome]
Taxonomic identifier242507 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeMagnaporthalesMagnaporthaceaeMagnaporthe

Protein attributes

Sequence length938 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 938938Probable dipeptidyl-aminopeptidase B
PRO_0000412147

Regions

Topological domain1 – 9999Cytoplasmic Potential
Transmembrane100 – 12021Helical; Signal-anchor for type II membrane protein; Potential
Topological domain121 – 938818Vacuolar Potential
Compositional bias56 – 616Poly-Asp

Sites

Active site7651Charge relay system By similarity
Active site8421Charge relay system By similarity
Active site8751Charge relay system By similarity

Amino acid modifications

Glycosylation2201N-linked (GlcNAc...) Potential
Glycosylation3601N-linked (GlcNAc...) Potential
Glycosylation8241N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A4QYQ5 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 394BD6652B2C8283

FASTA938105,281
        10         20         30         40         50         60 
MPVDKKSGNG RPSLDSVSSI STTSIVFDHL NDLEIHKKHR PHLMTESIRR DDHLSDFDDD 

        70         80         90        100        110        120 
DPLKQEMDGE GDLETGPFLA GRDAYTFGGG KYMDRKFRRI MIVVAGLLVA AWVGGLFVYI 

       130        140        150        160        170        180 
ASKSYKHATT VEHDPEKTKA AALTSGKKIT MDQVRSGTWY AASHDITWIA GPKGEDGLMI 

       190        200        210        220        230        240 
EVGADGKDYI VIEDGRAENP DSSAEAEVDV TASRRTLMKN GSFRYQGRMH IPSGAEPSRD 

       250        260        270        280        290        300 
QQKVLLRTEQ KSNWRHSHTA CYWIWDVATE TAEPLIPASP DARVQNAQWS PTSDAIVFTR 

       310        320        330        340        350        360 
ENNLYLRTIG SKKVTQITKD GGADLFYGVP DWVYEEEVIA GASTTWWSED GKYVAFLRTN 

       370        380        390        400        410        420 
ETGVPAFPVQ YFMSRPSGAS PKAGEETYPE VRDIKYPRSG SHNPVVDVQF YDIARGDVFT 

       430        440        450        460        470        480 
VDINGGFADE DRLITTVLWA GSQVIVKETN RVSDIMRVVL IDVKKRTGKT TRTVDVGKID 

       490        500        510        520        530        540 
GGWFEISQNT KYIPADPKKG RDQDGYIDTV IHNDGDHLAY FSPPDNPDPI MLTSGPGWEV 

       550        560        570        580        590        600 
VDAPSAVDLE NNLVYFIATK EGSTQRHVYS VQLDGKNMKS FTDTEAKGYY DVSFSSGAGY 

       610        620        630        640        650        660 
ALLSYKGPKI PWQKVVSTPA NNQRYEVLIE ENKELAESAR KYDLPLLNYG TLNVEGVELN 

       670        680        690        700        710        720 
YLERRPPQFS EKKKYPVLFH QYSGPGSQSV SQKFSVDFQS YVAASLGYIV VTFDGRGTGF 

       730        740        750        760        770        780 
IGRKNRVLVR SRLGEIEAQD QIAAAKHWAS LGYVDPSRIA IWGWSYGGFQ TLKTLEADAG 

       790        800        810        820        830        840 
RTFSYGMAVA PVTDWRFYDS IYTERYMLTP QQNEDGYTKS AVHNVSALAS NKRFLLMHGA 

       850        860        870        880        890        900 
SDDNVHFQNS LTLLDKLDMG AVENYDVHVF PDSDHSIFFH NANKIIYDKL ENWLVNAFNG 

       910        920        930 
EWLKVNNAKP VELVHPTQLV REREKAKLRK RWQEIQNK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM001233 Genomic DNA. Translation: EHA53149.1.
RefSeqXP_003712956.1. XM_003712908.1.

3D structure databases

ProteinModelPortalA4QYQ5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING148305.A4QYQ5.

Protein family/group databases

MEROPSS09.006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiMGG_07745T0; MGG_07745T0; MGG_07745.
GeneID2683672.
KEGGmgr:MGG_07745.

Phylogenomic databases

KOK01282.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMSSF53474. SSF53474. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDAPB_MAGO7
AccessionPrimary (citable) accession number: A4QYQ5
Secondary accession number(s): G4N0L8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: May 15, 2007
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries