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A4QPD7

- A4QPD7_MOUSE

UniProt

A4QPD7 - A4QPD7_MOUSE

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Protein
Submitted name:

Pms2 protein

Gene

Pms2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATPase activity Source: RefGenome
  2. ATP binding Source: InterPro
  3. single base insertion or deletion binding Source: Ensembl
  4. single-stranded DNA binding Source: RefGenome

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. cellular response to DNA damage stimulus Source: MGI
  3. DNA repair Source: MGI
  4. meiotic nuclear division Source: MGI
  5. mismatch repair Source: MGI
  6. response to drug Source: Ensembl
  7. somatic hypermutation of immunoglobulin genes Source: MGI
  8. somatic recombination of immunoglobulin gene segments Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_240368. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).
REACT_246095. Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta).

Names & Taxonomyi

Protein namesi
Submitted name:
Pms2 proteinImported
Gene namesi
Name:Pms2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104288. Pms2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. microtubule cytoskeleton Source: Ensembl
  3. MutLalpha complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiA4QPD7.
ExpressionAtlasiA4QPD7. baseline and differential.
GenevestigatoriA4QPD7.

Structurei

3D structure databases

ProteinModelPortaliA4QPD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000165474.

Family and domain databases

InterProiIPR014790. MutL_C.
IPR028831. Pms1/Pms2/PMS2L.
[Graphical view]
PANTHERiPTHR10073:SF9. PTHR10073:SF9. 1 hit.
PfamiPF08676. MutL_C. 1 hit.
[Graphical view]
SMARTiSM00853. MutL_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4QPD7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFAEMEILGQ FNLGFIVTKL KEDLFLVDQH AADEKYNFEM LQQHTVLQAQ
60 70 80 90 100
RLITPQTLNL TAVNEAVLIE NLEIFRKNGF DFVIDEDAPV TERAKLISLP
110 120 130 140 150
TSKNWTFGPQ DIDELIFMLS DSPGVMCRPS RVRQMFASRA CRKSVMIGTA
160 170 180 190
LNASEMKKLI THMGEMDHPW NCPHGRPTMR HVANLDVISQ N
Length:191
Mass (Da):21,792
Last modified:May 15, 2007 - v1
Checksum:iBCA4971E53EDAEE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139774 mRNA. Translation: AAI39775.1.
UniGeneiMm.2950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139774 mRNA. Translation: AAI39775.1 .
UniGenei Mm.2950.

3D structure databases

ProteinModelPortali A4QPD7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:104288. Pms2.

Phylogenomic databases

HOGENOMi HOG000165474.

Enzyme and pathway databases

Reactomei REACT_240368. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).
REACT_246095. Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta).

Miscellaneous databases

ChiTaRSi Pms2. mouse.
NextBioi 35544799.
SOURCEi Search...

Gene expression databases

Bgeei A4QPD7.
ExpressionAtlasi A4QPD7. baseline and differential.
Genevestigatori A4QPD7.

Family and domain databases

InterProi IPR014790. MutL_C.
IPR028831. Pms1/Pms2/PMS2L.
[Graphical view ]
PANTHERi PTHR10073:SF9. PTHR10073:SF9. 1 hit.
Pfami PF08676. MutL_C. 1 hit.
[Graphical view ]
SMARTi SM00853. MutL_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.

Entry informationi

Entry nameiA4QPD7_MOUSE
AccessioniPrimary (citable) accession number: A4QPD7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)