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Protein
Submitted name:

Proto-oncogene c-Rel

Gene

Rel

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-1169091. Activation of NF-kappaB in B cells.

Names & Taxonomyi

Protein namesi
Submitted name:
Proto-oncogene c-RelImported
Submitted name:
Reticuloendotheliosis oncogeneImported
Gene namesi
Name:RelImported
ORF Names:mCG_8770Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:97897. Rel.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000020275.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099928.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 182178RHD (Rel-like)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 RHD (Rel-like) domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IG8F. Eukaryota.
ENOG410XT64. LUCA.
GeneTreeiENSGT00500000044765.
HOGENOMiHOG000264257.
HOVERGENiHBG017916.
KOiK09254.
OMAiWEAKGIF.
OrthoDBiEOG091G08JD.
TreeFamiTF325632.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR030505. c-Rel.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030492. RHD_CS.
IPR032397. RHD_dimer.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF4. PTHR24169:SF4. 1 hit.
PfamiPF16179. RHD_dimer. 1 hit.
PF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
PRINTSiPR00057. NFKBTNSCPFCT.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4QPD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSGYNPYV EIIEQPRQRG MRFRYKCEGR SAGSIPGERS TDNNRTYPSV
60 70 80 90 100
QIMNYYGKGK IRITLVTKND PYKPHPHDLV GKDCRDGYYE AEFGPERRPL
110 120 130 140 150
FFQNLGIRCV KKKEVKEAII LRISAGINPF NVPEQQLLDI EDCDLNVVRL
160 170 180 190 200
CFQVFLPDEH GNFTTALPPI VSNPIYDNRA PNTAELRICR VNKNCGSVRG
210 220 230 240 250
GDEIFLLCDK VQKDDIEVRF VLNDWEARGV FSQADVHRQV AIVFKTPPYC
260 270 280 290 300
KAILEPVTVK MQLRRPSDQE VSESMDFRYL PDEKDAYGNK SKKQKTTLIF
310 320 330 340 350
QKLLQDCGHF TEKPRTAPLG STGEGRFIKK ESNLFSHGTV LPEMPRSSGV
360 370 380 390 400
PGQAEPYYSS CGSISSGLPH HPPAIPSVAH QPTSWPPVTH PTSHPVSTNT
410 420 430 440 450
LSTFSAGTLS SNSQGILPFL EGPGVSDLSA SNSCLYNPDD LARMETPSMS
460 470 480 490 500
PTDLYSISDV NMLSTRPLSV MAPSTDGMGD TDNPRLVSIN LENPSCNARL
510 520 530 540 550
GPRDLRQLHQ MSPASLSAGT SSSSVFVSQS DAFDRSNFSC VDNGLMNEPG
560 570 580
LSDDANNPTF VQSSHYSSVN TLQSEQLSDP FTYGFFKI
Length:588
Mass (Da):65,144
Last modified:February 5, 2008 - v1
Checksum:iD32CF1DF265F2AF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805916 Genomic DNA. No translation available.
BC139447 mRNA. Translation: AAI39448.1.
BC139448 mRNA. Translation: AAI39449.1.
BC139770 mRNA. Translation: AAI39771.1.
CH466595 Genomic DNA. Translation: EDL07897.1.
RefSeqiNP_033070.2. NM_009044.2.
UniGeneiMm.4869.

Genome annotation databases

EnsembliENSMUST00000102864; ENSMUSP00000099928; ENSMUSG00000020275.
GeneIDi19696.
KEGGimmu:19696.
UCSCiuc007ifo.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805916 Genomic DNA. No translation available.
BC139447 mRNA. Translation: AAI39448.1.
BC139448 mRNA. Translation: AAI39449.1.
BC139770 mRNA. Translation: AAI39771.1.
CH466595 Genomic DNA. Translation: EDL07897.1.
RefSeqiNP_033070.2. NM_009044.2.
UniGeneiMm.4869.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099928.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102864; ENSMUSP00000099928; ENSMUSG00000020275.
GeneIDi19696.
KEGGimmu:19696.
UCSCiuc007ifo.1. mouse.

Organism-specific databases

CTDi5966.
MGIiMGI:97897. Rel.

Phylogenomic databases

eggNOGiENOG410IG8F. Eukaryota.
ENOG410XT64. LUCA.
GeneTreeiENSGT00500000044765.
HOGENOMiHOG000264257.
HOVERGENiHBG017916.
KOiK09254.
OMAiWEAKGIF.
OrthoDBiEOG091G08JD.
TreeFamiTF325632.

Enzyme and pathway databases

ReactomeiR-MMU-1169091. Activation of NF-kappaB in B cells.

Miscellaneous databases

ChiTaRSiRel. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020275.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR030505. c-Rel.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030492. RHD_CS.
IPR032397. RHD_dimer.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF4. PTHR24169:SF4. 1 hit.
PfamiPF16179. RHD_dimer. 1 hit.
PF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
PRINTSiPR00057. NFKBTNSCPFCT.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4QPD3_MOUSE
AccessioniPrimary (citable) accession number: A4QPD3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.