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A4QND5 (NIP7_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
60S ribosome subunit biogenesis protein NIP7 homolog
Gene names
Name:nip7
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana

Protein attributes

Sequence length180 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly By similarity.

Subunit structure

Monomer. Interacts with pre-ribosome complex. May bind to RNA. Interacts with NOL8. Interacts with FTSJ3 By similarity.

Subcellular location

Nucleus › nucleolus By similarity.

Sequence similarities

Belongs to the NIP7 family.

Contains 1 PUA domain.

Ontologies

Keywords
   Biological processRibosome biogenesis
   Cellular componentNucleus
   LigandRNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processribosome assembly

Inferred from electronic annotation. Source: InterPro

   Cellular_componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 18018060S ribosome subunit biogenesis protein NIP7 homolog
PRO_0000355570

Regions

Domain94 – 17077PUA
Region1 – 9292N-terminal domain By similarity
Region93 – 18088C-terminal domain By similarity

Sequences

Sequence LengthMass (Da)Tools
A4QND5 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 2CD11D5321B5759E

FASTA18020,532
        10         20         30         40         50         60 
MRPLTDEETK AMFEKLSKYI GENIKLLVDR PDGTYCFRLH NDRVYYVSER ILKLATNIAR 

        70         80         90        100        110        120 
DKLVSLGTCF GKFTKTHKFR LHVTALDYLA PYAKYKVWVK PGAEQSFLYG NHVLKSGLGR 

       130        140        150        160        170        180 
ITENTSQYQG VVVYSMADIP LGFGVAAKST QECRKLDPMA IVVFHQADVG EYIRHEDTLT

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC135468 mRNA. Translation: AAI35469.1.
RefSeqNP_001096512.1. NM_001103042.1.
UniGeneStr.65697.

3D structure databases

ProteinModelPortalA4QND5.
SMRA4QND5. Positions 1-176.
ModBaseSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000038700.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSXETT00000038700; ENSXETP00000038700; ENSXETG00000017853.
GeneID100125143.
KEGGxtr:100125143.

Organism-specific databases

CTD51388.
XenbaseXB-GENE-1005412. nip7.

Phylogenomic databases

eggNOGCOG1374.
GeneTreeENSGT00390000003591.
HOGENOMHOG000168475.
HOVERGENHBG052625.
KOK07565.
OMAIVENSTH.
OrthoDBEOG45B1GK.

Gene expression databases

BgeeA4QND5.

Family and domain databases

InterProIPR002478. PUA.
IPR015947. PUA-like_domain.
IPR005155. Rbsml_synth_fac_NIP7-like.
IPR016686. Ribosomal_synth_fac_NIP7.
[Graphical view]
PANTHERPTHR23415:SF4. PTHR23415:SF4. 1 hit.
PfamPF03657. UPF0113. 1 hit.
[Graphical view]
PIRSFPIRSF017190. Rbsml_synth_fac_NIP7. 1 hit.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF88697. PUA-like. 1 hit.
PROSITEPS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNIP7_XENTR
AccessionPrimary (citable) accession number: A4QND5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: May 15, 2007
Last modified: April 3, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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