A4QN31 (A4QN31_DANRE) Unreviewed, UniProtKB/TrEMBL
Last modified
March 6, 2013.
Version 57.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Fibroblast growth factor receptor PIRNR PIRNR000628 EC=2.7.10.1 PIRNR PIRNR000628 | ||
| Gene names |
| ||
| Organism | Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAI34808.1 | ||
| Taxonomic identifier | 7955 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio![]() |
Protein attributes
| Sequence length | 728 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Catalytic activity | ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. PIRNR PIRNR000628 SAAS SAAS008266 |
| Sequence similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily. PIRNR PIRNR000628 Contains 1 protein kinase domain. SAAS SAAS008266 |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane |
| Domain | Immunoglobulin domain SAAS SAAS008266 Repeat SAAS SAAS008266 Transmembrane Transmembrane helix SAAS SAAS008266 |
| Ligand | ATP-binding PIRNR PIRNR000628 SAAS SAAS008266 Nucleotide-binding |
| Molecular function | Kinase Receptor PIRNR PIRNR000628 SAAS SAAS008266 Transferase Tyrosine-protein kinase PIRNR PIRNR000628 SAAS SAAS008266 |
| PTM | Phosphoprotein SAAS SAAS008266 |
| Gene Ontology (GO) | |
| Biological_process | positive regulation of cell proliferation Inferred from electronic annotation. Source: InterPro |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW fibroblast growth factor-activated receptor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 533 | 1 | Proton acceptor By similarity PIRSR PIRSR000628-1 | ||||||
Sequences
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References
| [1] | NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney EMBL AAI34808.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC134807 mRNA. Translation: AAI34808.1. |
| IPI | IPI00774172. |
| RefSeq | NP_001229935.1. NM_001243006.1. |
| UniGene | Dr.116399. Dr.31427. |
3D structure databases | |
| ProteinModelPortal | A4QN31. |
| SMR | A4QN31. Positions 63-273, 375-672. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A4QN31. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 352940. |
| KEGG | dre:352940. |
Organism-specific databases | |
| CTD | 2263. |
| ZFIN | ZDB-GENE-030323-1. fgfr2. |
Phylogenomic databases | |
| HOGENOM | HOG000263410. |
| HOVERGEN | HBG000345. |
| KO | K05093. |
Gene expression databases | |
| ArrayExpress | A4QN31. |
| Bgee | A4QN31. |
Family and domain databases | |
| Gene3D | 2.60.40.10. 2 hits. |
| InterPro | IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR013098. Ig_I-set. IPR003598. Ig_sub2. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR008266. Tyr_kinase_AS. IPR020635. Tyr_kinase_cat_dom. IPR016248. Tyr_kinase_fibroblast_GF_rcpt. [Graphical view] |
| Pfam | PF07679. I-set. 2 hits. PF07714. Pkinase_Tyr. 1 hit. [Graphical view] |
| PIRSF | PIRSF000628. FGFR. 1 hit. |
| PRINTS | PR00109. TYRKINASE. |
| SMART | SM00408. IGc2. 2 hits. SM00219. TyrKc. 1 hit. [Graphical view] |
| SUPFAM | SSF56112. Kinase_like. 1 hit. |
| PROSITE | PS50835. IG_LIKE. 2 hits. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 20812681. |
Entry information
| Entry name | A4QN31_DANRE | ||||||||
| Accession | Primary (citable) accession number: A4QN31 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
