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A4QIF6 (A4QIF6_CORGB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281
EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281
Ordered Locus Names:cgR_1452
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
A4QIF6 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 5CE540D572C534AE

FASTA35339,351
        10         20         30         40         50         60 
MREGLDYTVS EIQLTEASLN EAADAAIKAF DGAQNLDELA ALRRDHLGDA APIPQARRSL 

        70         80         90        100        110        120 
GTIPKDQRKD AGRFVNMALG RAEKHFAQVK VVLEEKRNAE VLELERVDVT VPTTREQVGA 

       130        140        150        160        170        180 
LHPITILNEQ IADIFVGMGW EIAEGPEVEA EYFNFDALNF LPDHPARTLQ DTFHIAPEGS 

       190        200        210        220        230        240 
RQVLRTHTSP VQVRTMLNRE VPIYIACPGR VFRTDELDAT HTPVFHQIEG LAVDKGLTMA 

       250        260        270        280        290        300 
HLRGTLDHLA KELFGPETKT RMRSNYFPFT EPSAEVDVWF PNKKGGAGWI EWGGCGMVNP 

       310        320        330        340        350 
NVLRAVGVDP EEYTGFAFGM GIERTLQFRN GLSDMRDMVE GDIRFTLPFG IQA

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009044 Genomic DNA. Translation: BAF54443.1.
RefSeqYP_001138345.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QIF6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4QIF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4991911.
GenomeReviewsGene locus cgR_1452 in contig AP009044_GR.
KEGGcgt:cgR_1452.
PATRIC21507486. VBICorGlu58097_1500.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0016.
HOGENOMHBG284353.
OMAFRASYFP.
ProtClustDBPRK00488.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4QIF6_CORGB
AccessionPrimary (citable) accession number: A4QIF6
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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