A4QHN8 (DCD_CORGB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	cgR_2737

Organism

Corynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]

Taxonomic identifier

340322 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009712

Sequences

	Sequence		Length	Mass (Da)
	A4QHN8 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: 820B4484A31A67EB	FASTA	189	20,689
	10 20 30 40 50 60 MLLSDRDIRK SIDAGDLGIE PFDAELIQPS SVDVRMDRYF RVFNNSKYTH IDPKLNQDEL 70 80 90 100 110 120 TSLVEVEDGE GFVLHPGEFV LASTLEKFTL PAHLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGYITLEL SNVANLPITL WPGMKVGQLA LFQMSSPAET PYGSGKLGSK YQGQRGPTPS KAYLNFPNK

References

[1]

"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R." Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M. Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: R.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009044 Genomic DNA. Translation: BAF55754.1.
RefSeq	YP_001139656.1. NC_009342.1.
3D structure databases
ProteinModelPortal	A4QHN8.
SMR	A4QHN8. Positions 1-186.
ModBase	Search...
Protein-protein interaction databases
STRING	A4QHN8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4993773.
GenomeReviews	Gene locus cgR_2737 in contig AP009044_GR.
KEGG	cgt:cgR_2737.
PATRIC	21510162. VBICorGlu58097_2803.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CORGB

Accession

Primary (citable) accession number: A4QHN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program