Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4QG77 (A4QG77_CORGB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:cgR_2239
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain314 – 38875PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A4QG77 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: A90FE821B0D8032E

FASTA40642,363
        10         20         30         40         50         60 
MTGLPVTPYS QEASIGASFP AVDPDTKDSA AYGHESGMRE RISNAKRVVV KIGSSSLTND 

        70         80         90        100        110        120 
EDGHTVDPNR INTIVNALQA RMEAGSDLIV VSSGAVAAGM APLGLSTRPT ELAVKQAAAA 

       130        140        150        160        170        180 
VGQVHLMHQW GRSFARYGRP IGQVLLTAAD AGKRDRARNA QRTIDKLRIL GAVPIVNEND 

       190        200        210        220        230        240 
TVATTGVNFG DNDRLAAIVA HLVSADALVL LSDVDGLFDK NPTDPTAKFI SEVRDGNDLK 

       250        260        270        280        290        300 
GVIAGDGGKV GTGGMASKVS AARLASRSGV PVLLTSAANI GPALEDAQVG TVFHPKDNRL 

       310        320        330        340        350        360 
SAWKFWALYA ADTAGKIRLD DGAVEAVTSG GKSLLAVGIT EIIGDFQQGE IVEILGPAGQ 

       370        380        390        400 
IIGRGEVSYD SDTLQSMVGM QTQDLPDGMQ RPVVHADYLS NYASRA

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009044 Genomic DNA. Translation: BAF55243.1.
RefSeqYP_001139145.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QG77.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4QG77.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4991813.
GenomeReviewsGene locus cgR_2239 in contig AP009044_GR.
KEGGcgt:cgR_2239.
PATRIC21509128. VBICorGlu58097_2306.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4QG77_CORGB
AccessionPrimary (citable) accession number: A4QG77
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info