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A4QFN1 (RSMH_CORGB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase H
EC=2.1.1.199
Alternative name(s):
16S rRNA m(4)C1402 methyltransferase
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Gene names
Name:rsmH
Synonyms:mraW
Ordered Locus Names:cgR_2048
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA By similarity. HAMAP MF_01007

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA. HAMAP MF_01007

Subcellular location

Cytoplasm By similarity HAMAP MF_01007.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmH family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 337337Ribosomal RNA small subunit methyltransferase H HAMAP MF_01007
PRO_0000386828

Regions

Region45 – 473S-adenosyl-L-methionine binding By similarity

Sites

Binding site641S-adenosyl-L-methionine By similarity
Binding site981S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding site1201S-adenosyl-L-methionine By similarity
Binding site1271S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
A4QFN1 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 0169ED8AF75A1D0C

FASTA33736,800
        10         20         30         40         50         60 
MEDFSLDGNH GHVPVMRDRM AALIAENVEA LGENAVIVDA TLGAGGHAEF FLNTFPKARL 

        70         80         90        100        110        120 
IGLDRDQNAL RDARARLAPF GERFIGVQTR FDGLREVLES VEGDIIDLAR EHGIAGALFD 

       130        140        150        160        170        180 
LGVSSMQLDQ VERGFAYRTD APLDMRMDAT QGITAADILN TYSHGDIARI LKTYGDERFA 

       190        200        210        220        230        240 
GKIASAVLKE REKEPFTTSA RLVELLYDAI PAATRRTGGH PAKRTFQALR VEVNNELDSL 

       250        260        270        280        290        300 
KNVLPQITDA LNVGGRAVFM SYQSHEDKLV KKFFTDLTTS KTPPGLPVDL PGTAPQFKQV 

       310        320        330 
TRGAETASEA EIEENPRAAP VKVRAIERIA NNSGDLS

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009044 Genomic DNA. Translation: BAF55047.1.
RefSeqYP_001138949.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QFN1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4QFN1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4992480.
GenomeReviewsGene locus cgR_2048 in contig AP009044_GR.
KEGGcgt:cgR_2048.
PATRIC21508728. VBICorGlu58097_2110.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0275.
HOGENOMHBG302779.
OMAGHVPVMR.
ProtClustDBPRK00050.

Family and domain databases

HAMAPMF_01007. 16SrRNA_methyltr_H.
[Tree]
InterProIPR002903. SAM-dep_MeTrfase_MraW.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
[Graphical view]
Gene3DG3DSA:1.10.150.170. G3DSA:1.10.150.170. 1 hit.
KOK03438.
PANTHERPTHR11265. Bact_methyltrans. 1 hit.
PfamPF01795. Methyltransf_5. 1 hit.
[Graphical view]
PIRSFPIRSF004486. MraW. 1 hit.
SUPFAMSSF81799. SSF81799. 1 hit.
TIGRFAMsTIGR00006. TIGR00006. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMH_CORGB
AccessionPrimary (citable) accession number: A4QFN1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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