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A4QFB7 (A4QFB7_CORGB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605
EC=2.1.1.228 HAMAP MF_00605
Alternative name(s):
M1G-methyltransferase HAMAP MF_00605
tRNA [GM37] methyltransferase HAMAP MF_00605
Gene names
Name:trmD HAMAP MF_00605
Ordered Locus Names:cgR_1937
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605

Catalytic activity

S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA. HAMAP MF_00605

Subunit structure

Homodimer By similarity. HAMAP MF_00605

Subcellular location

Cytoplasm By similarity HAMAP MF_00605.

Sequence similarities

Belongs to the RNA methyltransferase TrmD family. HAMAP MF_00605

Ontologies

Keywords
   Biological processtRNA processing HAMAP MF_00605
   Cellular componentCytoplasm HAMAP MF_00605
   LigandS-adenosyl-L-methionine HAMAP MF_00605
   Molecular functionMethyltransferase HAMAP MF_00605
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA (guanine-N1-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region181 – 1866S-adenosyl-L-methionine binding By similarity HAMAP MF_00605

Sites

Binding site1571S-adenosyl-L-methionine; via amide nitrogen By similarity HAMAP MF_00605

Sequences

Sequence LengthMass (Da)Tools
A4QFB7 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 9554CC53940F5319

FASTA28931,720
        10         20         30         40         50         60 
MTSSENLDSH RLRLDVVTIF PEYLDPLRHA LLGKAIEDGI LEVGVHDLRN WATGGHKAVD 

        70         80         90        100        110        120 
DTPYGGGPGM VMKPEVWGPA LDDVAAGRVS GAELDSASPH LKSARHDELG GVEKRAYVVE 

       130        140        150        160        170        180 
EDRDLPLLLV PTPAGKPFTQ ADAQAWSNEE HIVFACGRYE GIDQRVIDDA ANRYRVREVS 

       190        200        210        220        230        240 
IGDYVLIGGE VAVLVIAEAV VRLIPGVLGN RRSHEEDSFS DGLLEGPSYT KPRTWRGLDV 

       250        260        270        280 
PEVLFSGNHA KVDRWRRDQA LLRTQAIRPE LIDASLLDST DLKVLGLDK

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009044 Genomic DNA. Translation: BAF54933.1.
RefSeqYP_001138835.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QFB7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4QFB7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4992028.
GenomeReviewsGene locus cgR_1937 in contig AP009044_GR.
KEGGcgt:cgR_1937.
PATRIC21508498. VBICorGlu58097_1995.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0336.
HOGENOMHBG285805.
OMAVCGRFEG.
ProtClustDBPRK00026.

Family and domain databases

HAMAPMF_00605. TrmD.
[Tree]
InterProIPR016009. tRNA_m1G_MeTrfase.
IPR002649. tRNA_m1G_MeTrfase_bac.
IPR023148. tRNA_m1G_MeTrfase_C.
[Graphical view]
Gene3DG3DSA:1.10.1270.20. tRNA_m1G_MeTrfase_C. 1 hit.
KOK00554.
PANTHERPTHR10056. PTHR10056. 1 hit.
PfamPF01746. tRNA_m1G_MT. 2 hits.
[Graphical view]
PIRSFPIRSF000386. tRNA_mtase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4QFB7_CORGB
AccessionPrimary (citable) accession number: A4QFB7
Entry history
Integrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info