A4QEV1 (DAPF_CORGB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	cgR_1773

Organism

Corynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]

Taxonomic identifier

340322 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity HAMAP MF_00197.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000011872
Sites
	Active site	83	1	By similarity
	Active site	221	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4QEV1 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: A540184C69079066	FASTA	277	29,260
	10 20 30 40 50 60 MNLTIPFAKG HATENDFIII PDEDARLDLT PEMVVKLCDR RAGIGADGIL RVVKAADVEG 70 80 90 100 110 120 STVDPSLWFM DYRNADGSLA EMCGNGVRLF AHWLYSRSLV DNTSFDIGTR AGVRHVDILQ 130 140 150 160 170 180 ADQHSAQVRV DMGIPDVTGL STCDINGQVF AGLGVDMGNP HLACVVPGLS ASALADMELR 190 200 210 220 230 240 APTFDQEFFP HGVNVEIVTE LEDDAVSMRV WERGVGETRS CGTGTVAAAC AALADAGLGE 250 260 270 GTVKVCVPGG EVEVQIFDDG STLTGPSAII ALGEVQI

References

[1]

"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R." Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M. Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: R.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009044 Genomic DNA. Translation: BAF54767.1.
RefSeq	YP_001138669.1. NC_009342.1.
3D structure databases
ProteinModelPortal	A4QEV1.
ModBase	Search...
Protein-protein interaction databases
STRING	A4QEV1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4994319.
GenomeReviews	Gene locus cgR_1773 in contig AP009044_GR.
KEGG	cgt:cgR_1773.
PATRIC	21508156. VBICorGlu58097_1825.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0253.
HOGENOM	HBG399442.
OMA	FMTGPAT.
ProtClustDB	PRK00450.
Family and domain databases
HAMAP	MF_00197. DAP_epimerase. [Tree]
InterPro	IPR018510. DAP_epimerase_AS. IPR001653. DAP_epimerase_DapF. [Graphical view]
KO	K01778.
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_CORGB

Accession

Primary (citable) accession number: A4QEV1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program