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A4QEI3 (PYRF_CORGB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:cgR_1657
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000066468

Sites

Active site951Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A4QEI3 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: C601B3AE822133F3

FASTA27828,907
        10         20         30         40         50         60 
MTFGEKLLNA ASTRGRLCVG IDPHESLLTS WGLPVNVDGL AEFSRACVEA FADTVALVKP 

        70         80         90        100        110        120 
QVAFYERFGS AGFAILEETI QTLRERGCLV VSDAKRGDIG STMAGYASAW LDPASPLSSD 

       130        140        150        160        170        180 
AVTVSPYLGF HSLDPVFELA EQHGRGVFVL AATSNPEARE LQDQQNADGV SISQQIVDQA 

       190        200        210        220        230        240 
AALNAPYMAQ GKAGNIGVVI GATLSKPPRL STLGGAILMP GVGAQGGTAS DVDEIAGDMA 

       250        260        270 
HLAFPNVSRS ILATGPDIAE MKNSVAKTAA DFPGFPRS 

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009044 Genomic DNA. Translation: BAF54649.1.
RefSeqYP_001138551.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QEI3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340322.cgR_1657.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF54649; BAF54649; cgR_1657.
GeneID4992968.
KEGGcgt:cgR_1657.
PATRIC21507910. VBICorGlu58097_1706.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245748.
KOK01591.
OMADATHHLC.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycCGLU340322:GJBE-1731-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_CORGB
AccessionPrimary (citable) accession number: A4QEI3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 15, 2007
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways