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Protein

UvrABC system protein C

Gene

uvrC

Organism
Corynebacterium glutamicum (strain R)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:cgR_1640
OrganismiCorynebacterium glutamicum (strain R)
Taxonomic identifieri340322 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000006698 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000777761 – 696UvrABC system protein CAdd BLAST696

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA4QEG6.
SMRiA4QEG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 95GIY-YIGUniRule annotationAdd BLAST80
Domaini208 – 243UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279962.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

A4QEG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPTTYRPA PGTIPTEPGV YKFRDENRRV IYVGKAKNLR SRLSNYFQDV
60 70 80 90 100
TQLHPRTRQM VFAASSVEWT VVSSEVEALQ LEYTWIKRFD PRFNVKYRDD
110 120 130 140 150
KTYPMLAVST GERFPRAFFF RGPRRKGVRY FGPYSHAWAV RETLDLLTRV
160 170 180 190 200
FPMRTCSKGV FNRHESLGRP CLLGYIDKCA APCVGRVSEE EHREIVDGFT
210 220 230 240 250
SFMAGHTDKV TRKLNADMMA AAEELDFERA ARLRDDLEAI DKVMEKQAVV
260 270 280 290 300
LGDGTDADII AFATDQLEAA VQVFNIRGGR IRGQRGWVVD KPGDYAGLLV
310 320 330 340 350
DATTQPEGDA PETDPALPFL MQDFLVQFYG DAVERAETEA KEDAAVIERR
360 370 380 390 400
GVDKHSFEEA APVTRASVVP REILVQVAPN EAEQTLKVLE ELRGAGVDAR
410 420 430 440 450
VPQRGDKRAL METVERNAKE LLKQHKLKRV GDLTARSAAL QELQEALDME
460 470 480 490 500
QAPLRIECTD ISHIQGTDVV ASLVVFEDGL PRKSDYRRYR VKEAAGDGHS
510 520 530 540 550
NDVASIAEIT RRRFLRHNQD KLAVPEAEEF DGSTFSDEKV EEMSTDARRF
560 570 580 590 600
AYPPQIFIVD GGAPQVAAAQ EVFDELGIVD VVLIGLAKRL EEIWLPGDPD
610 620 630 640 650
PVILPRNSQA LFLLQQIRDE AHRFAITYHR QQRSKRMRVS ELDSIKGLGQ
660 670 680 690
SRRTELVKHF GSVAKLKEAS VEDISQVKGF GPKLAEAVYE GLHASK
Length:696
Mass (Da):78,334
Last modified:May 15, 2007 - v1
Checksum:iE742491E15C38A8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009044 Genomic DNA. Translation: BAF54632.1.
RefSeqiWP_011897303.1. NC_009342.1.

Genome annotation databases

EnsemblBacteriaiBAF54632; BAF54632; cgR_1640.
KEGGicgt:cgR_1640.

Similar proteinsi

Entry informationi

Entry nameiUVRC_CORGB
AccessioniPrimary (citable) accession number: A4QEG6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 15, 2007
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families