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A4QEG1 (PGK_CORGB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase
EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:cgR_1635
OrganismCorynebacterium glutamicum (strain R) [Complete proteome] [HAMAP]
Taxonomic identifier340322 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145

Subunit structure

Monomer By similarity. HAMAP MF_00145

Subcellular location

Cytoplasm Potential HAMAP MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Phosphoglycerate kinase HAMAP MF_00145
PRO_1000009612

Regions

Nucleotide binding361 – 3644ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1221Substrate By similarity
Binding site1621Substrate By similarity
Binding site2121ATP By similarity
Binding site3311ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A4QEG1 [UniParc].

Last modified May 15, 2007. Version 1.
Checksum: 2728CD4294E9F0F3

FASTA40542,755
        10         20         30         40         50         60 
MAVKTLKDLL DEGVDGRHVI VRSDFNVPLN DDREITDKGR IIASLPTLKA LSEGGAKVIV 

        70         80         90        100        110        120 
MAHLGRPKGE VNEKYSLAPV AEALSDELGQ YVALAADVVG EDAHERANGL TEGDILLLEN 

       130        140        150        160        170        180 
VRFDPRETSK DEAERTAFAQ ELAALAADNG AFVSDGFGVV HRAQTSVYDI AKLLPHYAGG 

       190        200        210        220        230        240 
LVETEISVLE KIAESPEAPY VVVLGGSKVS DKIGVIEALA AKADKIIVGG GMCYTFLAAQ 

       250        260        270        280        290        300 
GHNVQQSLLQ EEMKETCTDL LARFGDKIVL PVDLVAASEF NKDAEKQIVD LDSIPEGWMS 

       310        320        330        340        350        360 
LDIGPESVKN FGEVLSTAKT IFWNGPMGVF EFAAFSEGTR GIAQAIIDAT AGNDAFSVVG 

       370        380        390        400 
GGDSAASVRV LGLNEDGFSH ISTGGGASLE YLEGKELPGV AILAQ

« Hide

References

[1]"Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
Microbiology 153:1042-1058(2007) [PubMed: 17379713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009044 Genomic DNA. Translation: BAF54627.1.
RefSeqYP_001138529.1. NC_009342.1.

3D structure databases

ProteinModelPortalA4QEG1.
SMRA4QEG1. Positions 4-404.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4QEG1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4992885.
GenomeReviewsGene locus cgR_1635 in contig AP009044_GR.
KEGGcgt:cgR_1635.
PATRIC21507866. VBICorGlu58097_1684.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHBG453500.
OMAAKPMAAI.
ProtClustDBPRK00073.

Family and domain databases

HAMAPMF_00145. Phosphoglyc_kinase.
[Tree]
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit.
G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KOK00927.
PANTHERPTHR11406. PGK. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. PGK. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CORGB
AccessionPrimary (citable) accession number: A4QEG1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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