Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A4QBP2

- A4QBP2_CORGB

UniProt

A4QBP2 - A4QBP2_CORGB

Protein

Protein translocase subunit SecY

Gene

secY

Organism
Corynebacterium glutamicum (strain R)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (15 May 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.UniRule annotation

    GO - Biological processi

    1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
    2. protein targeting Source: UniProtKB-HAMAP
    3. protein transport by the Sec complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, TranslocationUniRule annotation, Transport

    Enzyme and pathway databases

    BioCyciCGLU340322:GJBE-700-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein translocase subunit SecYUniRule annotation
    Gene namesi
    Name:secYUniRule annotation
    Ordered Locus Names:cgR_0668Imported
    OrganismiCorynebacterium glutamicum (strain R)Imported
    Taxonomic identifieri340322 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000006698: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
    Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. intracellular Source: GOC
    3. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneUniRule annotation, Membrane

    Interactioni

    Subunit structurei

    Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

    Protein-protein interaction databases

    STRINGi340322.cgR_0668.

    Structurei

    3D structure databases

    ProteinModelPortaliA4QBP2.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei17 – 3721Helical;UniRule annotationAdd
    BLAST
    Transmembranei74 – 9421Helical;UniRule annotationAdd
    BLAST
    Transmembranei116 – 13520Helical;UniRule annotationAdd
    BLAST
    Transmembranei155 – 17521Helical;UniRule annotationAdd
    BLAST
    Transmembranei178 – 19821Helical;UniRule annotationAdd
    BLAST
    Transmembranei213 – 23321Helical;UniRule annotationAdd
    BLAST
    Transmembranei270 – 29021Helical;UniRule annotationAdd
    BLAST
    Transmembranei316 – 33621Helical;UniRule annotationAdd
    BLAST
    Transmembranei374 – 39421Helical;UniRule annotationAdd
    BLAST
    Transmembranei403 – 42321Helical;UniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SecY/SEC61-alpha family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    eggNOGiCOG0201.
    HOGENOMiHOG000080586.
    KOiK03076.
    OMAiAWNVQFY.
    OrthoDBiEOG651SWP.

    Family and domain databases

    Gene3Di1.10.3370.10. 1 hit.
    HAMAPiMF_01465. SecY.
    InterProiIPR026593. SecY.
    IPR002208. SecY/SEC61-alpha.
    IPR023201. SecY_su_dom.
    [Graphical view]
    PANTHERiPTHR10906. PTHR10906. 1 hit.
    PfamiPF00344. SecY. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004557. SecY. 1 hit.
    SUPFAMiSSF103491. SSF103491. 1 hit.
    TIGRFAMsiTIGR00967. 3a0501s007. 1 hit.
    PROSITEiPS00755. SECY_1. 1 hit.
    PS00756. SECY_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4QBP2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAIIQAFKD ADLRKKIFFT IAMIVLYRIG AQIPSPGVDY ATISGRLRDL    50
    TQDQSSVYSL INLFSGGALL QLSIFAIGIM PYITASIIVQ LLTVVIPHFE 100
    ELKKEGQSGQ AKMMQYTRYL TVALALLQSS GIVALADREQ LLGAGIRVLS 150
    ADRNFFDLIV LVITMTAGAV LVMWMGELIT EKGVGNGMSL LIFAGIATRL 200
    PTDGMNILGN SGGVVFAVVL ASVLILVIGV VFVEQGQRRI PVQYAKRMVG 250
    RRQYGGSSTY LPLKVNQAGV IPVIFASSLI YMPVLITQIV NSGSLEVSDN 300
    WWQRNIIAHL QTPSSWQYIV LYFALTIFFS YFYVSVQYDP AEQAENMKKY 350
    GGFIPGIRPG RPTAEYLGFV MNRLLFVGSL YLAVIAVLPN IMLDLGVDAG 400
    SAGATPFGGT AILILVSVAL TTVKQIESQL LQSNYEGLLK 440
    Length:440
    Mass (Da):47,903
    Last modified:May 15, 2007 - v1
    Checksum:i3C8871F57A6825E2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009044 Genomic DNA. Translation: BAF53639.1.
    RefSeqiYP_001137541.1. NC_009342.1.

    Genome annotation databases

    EnsemblBacteriaiBAF53639; BAF53639; cgR_0668.
    GeneIDi4992289.
    KEGGicgt:cgR_0668.
    PATRICi21505843. VBICorGlu58097_0696.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009044 Genomic DNA. Translation: BAF53639.1 .
    RefSeqi YP_001137541.1. NC_009342.1.

    3D structure databases

    ProteinModelPortali A4QBP2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 340322.cgR_0668.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAF53639 ; BAF53639 ; cgR_0668 .
    GeneIDi 4992289.
    KEGGi cgt:cgR_0668.
    PATRICi 21505843. VBICorGlu58097_0696.

    Phylogenomic databases

    eggNOGi COG0201.
    HOGENOMi HOG000080586.
    KOi K03076.
    OMAi AWNVQFY.
    OrthoDBi EOG651SWP.

    Enzyme and pathway databases

    BioCyci CGLU340322:GJBE-700-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3370.10. 1 hit.
    HAMAPi MF_01465. SecY.
    InterProi IPR026593. SecY.
    IPR002208. SecY/SEC61-alpha.
    IPR023201. SecY_su_dom.
    [Graphical view ]
    PANTHERi PTHR10906. PTHR10906. 1 hit.
    Pfami PF00344. SecY. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004557. SecY. 1 hit.
    SUPFAMi SSF103491. SSF103491. 1 hit.
    TIGRFAMsi TIGR00967. 3a0501s007. 1 hit.
    PROSITEi PS00755. SECY_1. 1 hit.
    PS00756. SECY_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R."
      Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.
      Microbiology 153:1042-1058(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RImported.

    Entry informationi

    Entry nameiA4QBP2_CORGB
    AccessioniPrimary (citable) accession number: A4QBP2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 15, 2007
    Last sequence update: May 15, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3