A4LD03 (A4LD03_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL EBA51639.1
ORF Names:	BURPS305_7155 EMBL EBA51639.1

Organism

Burkholderia pseudomallei 305 EMBL EBA51639.1

Taxonomic identifier

425067 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EBA51639.1

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL EBA51639.1
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	156	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A4LD03 [UniParc]. Last modified May 15, 2007. Version 1. Checksum: BEE6B7EDC0290628	FASTA	263	27,771
	10 20 30 40 50 60 MGFLDGKRIL LTGLLSNRSI AYGIAKACKR EGAELAFTYV GDRFKDRITE FAAEFGSELV 70 80 90 100 110 120 FPCDVADDAQ IDALFASLKT HWDSLDGLVH SIGFAPREAI AGDFLDGLTR ENFRIAHDIS 130 140 150 160 170 180 AYSFPALAKA ALPMLSDDAS LLTLSYLGAE RAIPNYNTMG LAKAALEASV RYLAVSLGAK 190 200 210 220 230 240 GVRVNAISAG PIKTLAASGI KSFGKILDFV ESNSPLKRNV TIEQVGNAGA FLLSDLASGV 250 260 TAEVMHVDSG FNAVVGGMAG LEE

References

[1]	Nelson W.C., Wagner D., Currie B., Tuanyok A., Mayo M., Schupp J., Lum G., Keim P., Brettin T. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 305 EMBL EBA51639.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAYX01000001 Genomic DNA. Translation: EBA51639.1.
3D structure databases
ProteinModelPortal	A4LD03.
SMR	A4LD03. Positions 2-262.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	27851630. VBIBurPse67809_0566.
Phylogenomic databases
OMA	KKWDGLD.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

A4LD03_BURPS

Accession

Primary (citable) accession number: A4LD03

Entry history

Integrated into UniProtKB/TrEMBL:	May 15, 2007
Last sequence update:	May 15, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)