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A4KHY6 (A4KHY6_MYCTU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length741 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641 RuleBase RU003572 SAAS SAAS006253

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641 RuleBase RU003572 SAAS SAAS006253

Subunit structure

Monomer By similarity. HAMAP MF_00641 SAAS SAAS006253

Subcellular location

Cytoplasm By similarity HAMAP MF_00641 RuleBase RU003572.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily. HAMAP MF_00641 RuleBase RU003572

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3391Proton acceptor By similarity HAMAP MF_00641
Active site6331Proton donor By similarity HAMAP MF_00641

Sequences

Sequence LengthMass (Da)Tools
A4KHY6 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: A92F54E0FE8B7C64

FASTA74180,403
        10         20         30         40         50         60 
MTDRVSVGNL RIARVLYDFV NNEALPGTDI DPDSFWAGVD KVVADLTPQN QALLNARDEL 

        70         80         90        100        110        120 
QAQIDKWHRR RVIEPIDMDA YRQFLTEIGY LLPEPDDFTI TTSGVDAEIT TTAGPQLVVP 

       130        140        150        160        170        180 
VLNARFALNA ANARWGSLYD ALYGTDVIPE TDGAEKGPTY NKVRGDKVIA YARKFLDDSV 

       190        200        210        220        230        240 
PLSSGSFGDA TGFTVQDGQL VVALPDKSTG LANPGQFAGY TGAAESPTSV LLINHGLHIE 

       250        260        270        280        290        300 
ILIDPESQVG TTDRAGVKDV ILESAITTIM DFEDSVAAVD AADKVLGYRN WLGLNKGDLA 

       310        320        330        340        350        360 
AAVDKDGTAF LRVLNRDRNY TAPGGGQFTL PGRSLMFVRN VGHLMTNDAI VDTDGSEVFE 

       370        380        390        400        410        420 
GIMDALFTGL IAIHGLKASD VNGPLINSRT GSIYIVKPKM HGPAEVAFTC ELFSRVEDVL 

       430        440        450        460        470        480 
GLPQNTMKIG IMDEERRTTV NLKACIKAAA DRVVFINTGF LDRTGDEIHT SMEAGPMVRK 

       490        500        510        520        530        540 
GTMKSQPWIL AYEDHNVDAG LAAGFSGRAQ VGKGMWTMTE LMADMVETKI AQPRAGASTA 

       550        560        570        580        590        600 
WVPSPTAATL HALHYHQVDV AAVQQGLAGK RRATIEQLLT IPLAKELAWA PDEIREEVDN 

       610        620        630        640        650        660 
NCQSILGYVV RWVDQGVGCS KVPDIHDVAL MEDRATLRIS SQLLANWLRH GVITSADVRA 

       670        680        690        700        710        720 
SLERMAPLVD RQNAGDVAYR PMAPNFDDSI AFLAAQELIL SGAQQPNGYT EPILHRRRRE 

       730        740 
FKARAAEKPA PSDRAGDDAA R

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS016976 Genomic DNA. Translation: EBA42221.1.

3D structure databases

ProteinModelPortalA4KHY6.
SMRA4KHY6. Positions 5-727.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC30816443. VBIMycTub106824_1482.

Phylogenomic databases

OMAPKMHGPD.

Family and domain databases

HAMAPMF_00641. Malate_synth_G.
[Tree]
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
Gene3DG3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
PANTHERPTHR21631:SF1. Malate_synthase. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. Malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4KHY6_MYCTU
AccessionPrimary (citable) accession number: A4KHY6
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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