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Protein

Beta-lactamase

Gene

BlaGIL-1

Organism
Citrobacter gillenii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processAntibiotic resistanceUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseUniRule annotationSAAS annotation (EC:3.5.2.6UniRule annotationSAAS annotation)
Gene namesi
Name:BlaGIL-1Imported
OrganismiCitrobacter gilleniiImported
Taxonomic identifieri67828 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCitrobacterCitrobacter freundii complex

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1075063.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500267160422 – 286Beta-lactamaseSequence analysisAdd BLAST265

Interactioni

Chemistry databases

BindingDBiA4KCT8.

Structurei

3D structure databases

ProteinModelPortaliA4KCT8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A.
IPR023650. Beta-lactam_class-A_AS.
PRINTSiPR00118. BLACTAMASEA.
SUPFAMiSSF56601. SSF56601. 1 hit.
PROSITEiView protein in PROSITE
PS00146. BETA_LACTAMASE_A. 1 hit.

Sequencei

Sequence statusi: Complete.

A4KCT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPHFRLALIP LLTAFCLPAF AHPTTLNKVK EAESQLTARV GYAELDLTSG
60 70 80 90 100
EILESYRLQE RFPMMSTFKV LLCGAVLARV DAGKERLDRR IPFSRRDLVE
110 120 130 140 150
YSPVTEKHLT DGMTVGELCD AAITMSDNTA ANLLLTAIGG PQGLTAFLRT
160 170 180 190 200
TGDRVTRLDR WEPELNEALP GDKRDTTTPE NMAQTLRQLL TGKILTTTSQ
210 220 230 240 250
QQLTHWMVTD KVAGPLLRSV LPAGWFIADK TGAGARGSRG IVAALGPDGK
260 270 280
PSRIVVIYIT ESQATMAERN RQIAGIGATL IQHWDE
Length:286
Mass (Da):31,367
Last modified:May 1, 2007 - v1
Checksum:i9E0CE84C6EE3FC92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ991234 Genomic DNA. Translation: ABL74511.1.
RefSeqiWP_063860521.1. NG_049142.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ991234 Genomic DNA. Translation: ABL74511.1.
RefSeqiWP_063860521.1. NG_049142.1.

3D structure databases

ProteinModelPortaliA4KCT8.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiA4KCT8.
ChEMBLiCHEMBL1075063.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A.
IPR023650. Beta-lactam_class-A_AS.
PRINTSiPR00118. BLACTAMASEA.
SUPFAMiSSF56601. SSF56601. 1 hit.
PROSITEiView protein in PROSITE
PS00146. BETA_LACTAMASE_A. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA4KCT8_9ENTR
AccessioniPrimary (citable) accession number: A4KCT8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: March 15, 2017
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.