A4K9Z8 (A4K9Z8_BETPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Profilin RuleBase RU003909
Organism	Betula pendula (European white birch) (Betula verrucosa) EMBL ABG48509.1
Taxonomic identifier	3505 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fagales › Betulaceae › Betula

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By similarity. RuleBase RU003908
Subunit structure	Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio By similarity. RuleBase RU003908
Sequence similarities	Belongs to the profilin family. RuleBase RU003909

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton SAAS SAAS002097 RuleBase RU003908
Ligand	Actin-binding SAAS SAAS002097 RuleBase RU003909
Gene Ontology (GO)
Biological_process	actin cytoskeleton organization Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4K9Z8 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 50E3A0EA509A9261	FASTA	133	14,278
	10 20 30 40 50 60 MSWQTYVDEH LMCDIDGQGQ QLAASAIVGH DGSVWAQSSS FPQFKPQEIT GIMKDFEEPG 70 80 90 100 110 120 HLAPTGLHLG GIKYMVIQGE AGAVIRGKKG SGGITIKKTG QALVFGIYEE PVTPGQCNMV 130 VERLGDYLID QGL

References

[1]	"Characterization of profilin polymorphism in pollen with a focus on multifunctionality." Jimenez-Lopez J.C., Morales S., Castro A.J., Volkmann D., Rodriguez-Garcia M.I., Alche Jde D. PLoS ONE 7:E30878-E30878(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ650633 mRNA. Translation: ABG48509.1.
3D structure databases
ProteinModelPortal	A4K9Z8.
SMR	A4K9Z8. Positions 2-133.
ModBase	Search...
Protein family/group databases
Allergome	127. Bet v 2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR027310. Profilin_CS. IPR005455. Profilin_eukaryotes/bac. [Graphical view]
PANTHER	PTHR11604. PTHR11604. 1 hit.
Pfam	PF00235. Profilin. 1 hit. [Graphical view]
PRINTS	PR00392. PROFILIN. PR01640. PROFILINPLNT.
SMART	SM00392. PROF. 1 hit. [Graphical view]
SUPFAM	SSF55770. Profilin. 1 hit.
PROSITE	PS00414. PROFILIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4K9Z8_BETPN

Accession

Primary (citable) accession number: A4K9Z8

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)