ID   A4JTH0_BURVG            Unreviewed;       499 AA.
AC   A4JTH0;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE            EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN   OrderedLocusNames=Bcep1808_6684 {ECO:0000313|EMBL:ABO59573.1};
OS   Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia
OS   (strain R1808)).
OG   Plasmid pBVIE01 {ECO:0000313|EMBL:ABO59573.1,
OG   ECO:0000313|Proteomes:UP000002287}.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=269482 {ECO:0000313|EMBL:ABO59573.1, ECO:0000313|Proteomes:UP000002287};
RN   [1] {ECO:0000313|EMBL:ABO59573.1, ECO:0000313|Proteomes:UP000002287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G4 / LMG 22486 {ECO:0000313|Proteomes:UP000002287};
RC   PLASMID=pBVIE01 {ECO:0000313|EMBL:ABO59573.1,
RC   ECO:0000313|Proteomes:UP000002287};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Tiedje J., Richardson P.;
RT   "Complete sequence of plasmid pBVIE01 of Burkholderia vietnamiensis G4.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000617; ABO59573.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4JTH0; -.
DR   KEGG; bvi:Bcep1808_6684; -.
DR   HOGENOM; CLU_005391_1_2_4; -.
DR   Proteomes; UP000002287; Plasmid pBVIE01.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07130; ALDH_F7_AASADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR044638; ALDH7A1-like.
DR   PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}; Plasmid {ECO:0000313|EMBL:ABO59573.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002287}.
FT   DOMAIN          19..477
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        252
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   499 AA;  52957 MW;  815DC28F30637EF4 CRC64;
     MKASTILSDL GIAHLAGAGD IEVRSPINGE VVGRVASQTV SDVDAALASA QEAYKAWRNV
     PAPRRGELVR LLGEKLREQK QALGSIITLE TGKILQEGLG EVQEMIDICD FAVGLSRQLY
     GLTIASERPG HRMAETWHPM GVCTVISAFN FPAAVWSWNA ALALVCGNAV IWKPSEKTPL
     TALAVDKILH DALKEFGDAP AGLTALINGG RDVGAKLVSD SRSNIVSATG STEMGRAVGI
     EVARRFGRSL LELGGNNAGI VSNTADLELA LRGILFSAVG TAGQRCTTLR RLFVQESIYD
     KVVDRLKTFY AKVAIGNPLE QGTLMGPLID GQSFSRMQAA LEQAKSEGGK VFGGERHVVA
     GNENGFYVRP AIVEMPSQTD IVLQETFAPI LYVLKYSDFN EALEANNAAH HGLSSCVFTT
     DLRESERFLS ASGSDCGIAN VNIGPSGAEI GGAFGGEKET GGGRESGSDA WKAYMRRATN
     TVNFSSALPL AQGIDFNID
//