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Protein

Aspartate ammonia-lyase

Gene

Bcep1808_4633

Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-4716-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyaseUniRule annotation (EC:4.3.1.1UniRule annotation)
Short name:
AspartaseUniRule annotation
Gene namesi
Ordered Locus Names:Bcep1808_4633Imported
OrganismiBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))Imported
Taxonomic identifieri269482 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002287 Componenti: Chromosome 2

Interactioni

Protein-protein interaction databases

STRINGi269482.Bcep1808_4633.

Structurei

3D structure databases

ProteinModelPortaliA4JMU1.
SMRiA4JMU1. Positions 1-458.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 345332Lyase_1InterPro annotationAdd
BLAST
Domaini411 – 46353FumaraseC_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiPOG091H01XG.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4JMU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTERGFRVEA DLLGQRNVPD SAYYGVHTLR AQENFDISGR TIASLPYLVV
60 70 80 90 100
ALAAVKEAAA DANCELGLLP RAYRDAIAAA CAEIRDGRLH DQFVVDVIQG
110 120 130 140 150
GAGTSTNMNA NEVICNRALE IMGHARGQYE HLHPNEHVNL AQSTNDVYPT
160 170 180 190 200
AIRIATCFAV EQLLEAMAHL RDAFAQKADA FADLLKLGRT QLQDAVPMTL
210 220 230 240 250
GQEFSTYAVM VSEDIARLQE AGWLMREINL GATAIGTGIT AHPDYAAKAL
260 270 280 290 300
AALRRITGLD LSTAPNLIEA TQDCGAFVQM SGVLKRIAVK LSKICNDLRL
310 320 330 340 350
LSSGPRAGFG EINLPPVQAG SSIMPGKVNP VIPEVVNQVA FEVFGNDLTV
360 370 380 390 400
TFAAEAGQLQ LNAFEPVIAS ALFRSFGHLS AACTTLADRC VSGITANPER
410 420 430 440 450
LRDTMERSVA LATALNPYIG YKRATAVAKE AHESGKSIRE VVLEHRLMTD
460
AQLDDALQPE ALIRPRAY
Length:468
Mass (Da):50,421
Last modified:May 1, 2007 - v1
Checksum:i52C46A4CCB10F4CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000615 Genomic DNA. Translation: ABO57594.1.
RefSeqiWP_011881925.1. NC_009255.1.

Genome annotation databases

EnsemblBacteriaiABO57594; ABO57594; Bcep1808_4633.
KEGGibvi:Bcep1808_4633.
PATRICi19316663. VBIBurVie89221_3346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000615 Genomic DNA. Translation: ABO57594.1.
RefSeqiWP_011881925.1. NC_009255.1.

3D structure databases

ProteinModelPortaliA4JMU1.
SMRiA4JMU1. Positions 1-458.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269482.Bcep1808_4633.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO57594; ABO57594; Bcep1808_4633.
KEGGibvi:Bcep1808_4633.
PATRICi19316663. VBIBurVie89221_3346.

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.
OrthoDBiPOG091H01XG.

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-4716-MONOMER.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4JMU1_BURVG
AccessioniPrimary (citable) accession number: A4JMU1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.