A4JJG6 (BETA_BURVG) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 36.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Choline dehydrogenase Short name=CDH Short name=CHD EC=1.1.99.1 | ||||
| Gene names |
| ||||
| Organism | Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808)) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 269482 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex |
Protein attributes
| Sequence length | 566 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750 |
| Catalytic activity | Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750 |
| Cofactor | FAD By similarity. HAMAP MF_00750 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750 |
| Sequence similarities | Belongs to the GMC oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro |
| Molecular function | choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 566 | 566 | Choline dehydrogenase HAMAP MF_00750 | PRO_1000046561 | |||||
Regions | |||||||||
| Nucleotide binding | 7 – 36 | 30 | FAD Potential | ||||||
Sites | |||||||||
| Active site | 474 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of chromosome 2 of Burkholderia vietnamiensis G4." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. Richardson P.Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: G4 / LMG 22486. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000615 Genomic DNA. Translation: ABO56419.1. |
| RefSeq | YP_001115884.1. NC_009255.1. |
3D structure databases | |
| ProteinModelPortal | A4JJG6. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A4JJG6. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4949643. |
| GenomeReviews | Gene locus Bcep1808_3431 in contig CP000615_GR. |
| KEGG | bvi:Bcep1808_3431. |
| PATRIC | 19314196. VBIBurVie89221_2116. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG2303. |
| HOGENOM | HBG734713. |
| OMA | RSTAPYY. |
| ProtClustDB | PRK02106. |
Enzyme and pathway databases | |
| BioCyc | BVIE269482:BCEP1808_3431-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00750. Choline_dehydrogen. [Tree] |
| InterPro | IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view] |
| KO | K00108. |
| Pfam | PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000137. Alcohol_oxidase. 1 hit. |
| TIGRFAMs | TIGR01810. BetA. 1 hit. |
| PROSITE | PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETA_BURVG | ||||||||
| Accession | Primary (citable) accession number: A4JJG6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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