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A4JJF8 (A4JJF8_BURVG) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 2 HAMAP MF_00051
Short name=SHMT 2 HAMAP MF_00051
Short name=Serine methylase 2 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA2 HAMAP MF_00051
Ordered Locus Names:Bcep1808_3423
OrganismBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808)) [Complete proteome] [HAMAP] EMBL ABO56411.1
Taxonomic identifier269482 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2341N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
A4JJF8 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 4197F83737B6BB38

FASTA42445,634
        10         20         30         40         50         60 
MSNTQPFFSQ PLAERDAPVR SAILKELERQ QSQVELIASE NIVSRAVLEA QGSVLTNKYA 

        70         80         90        100        110        120 
EGYPGKRYYG GCEFADEIEA LAIERVKQIF NAGYANVQPH SGAQANGSVM LALAKPGDTV 

       130        140        150        160        170        180 
LGMSLDAGGH LTHGAKPALS GKWFNAVQYG VNRDTMRIDY DQVEELAHQH KPTLLIAGFS 

       190        200        210        220        230        240 
AYPRALDFAR FRAIADSVGA KLMVDMAHIA GVIAAGRHAN PVEHAHVVTS TTHKTLRGPR 

       250        260        270        280        290        300 
GGFVLTNDEE IAKKINSAVF PGLQGGPLMH VIAGKAVAFG EVLHADFKTY IDRVLANAQA 

       310        320        330        340        350        360 
LGEVLKAGGV DLVTGGTDNH LLLVDLRPKG LKGAPVEQAL ERAGITCNKN GIPFDTEKPT 

       370        380        390        400        410        420 
VTSGIRLGTP AGTTRGFGVA EFREIGRLIL EVFDALRANP DGDHATEQRV RREIFALCER 


FPIY

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia vietnamiensis G4."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Tiedje J., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: G4 / LMG 22486.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000615 Genomic DNA. Translation: ABO56411.1.
RefSeqYP_001115876.1. NC_009255.1.

3D structure databases

ProteinModelPortalA4JJF8.
SMRA4JJF8. Positions 12-389.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4JJF8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4949635.
GenomeReviewsGene locus Bcep1808_3423 in contig CP000615_GR.
KEGGbvi:Bcep1808_3423.
PATRIC19314176. VBIBurVie89221_2106.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMAIFNAGYA.
ProtClustDBPRK13034.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4JJF8_BURVG
AccessionPrimary (citable) accession number: A4JJF8
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info