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A4JIV2

- A4JIV2_BURVG

UniProt

A4JIV2 - A4JIV2_BURVG

Protein

Glucose-1-phosphate thymidylyltransferase

Gene

Bcep1808_3215

Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 May 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.UniRule annotation

    Catalytic activityi

    dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose.UniRule annotation

    GO - Molecular functioni

    1. glucose-1-phosphate thymidylyltransferase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. extracellular polysaccharide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    NucleotidyltransferaseUniRule annotationImported, Transferase

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciBVIE269482:GJNA-3288-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-1-phosphate thymidylyltransferaseUniRule annotation (EC:2.7.7.24UniRule annotation)
    Gene namesi
    Ordered Locus Names:Bcep1808_3215Imported
    OrganismiBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))Imported
    Taxonomic identifieri269482 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
    ProteomesiUP000002287: Chromosome 1

    Interactioni

    Protein-protein interaction databases

    STRINGi269482.Bcep1808_3215.

    Structurei

    3D structure databases

    ProteinModelPortaliA4JIV2.
    SMRiA4JIV2. Positions 3-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glucose-1-phosphate thymidylyltransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1209.
    HOGENOMiHOG000283473.
    KOiK00973.
    OMAiFIVGRDF.
    OrthoDBiEOG6RC3RN.

    Family and domain databases

    Gene3Di3.90.550.10. 1 hit.
    InterProiIPR005907. G1P_thy_trans_s.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view]
    PANTHERiPTHR22572:SF13. PTHR22572:SF13. 1 hit.
    PfamiPF00483. NTP_transferase. 1 hit.
    [Graphical view]
    SUPFAMiSSF53448. SSF53448. 1 hit.
    TIGRFAMsiTIGR01207. rmlA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4JIV2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTQRKGIILA GGSGTRLHPA TLAISKQLLP VYDKPMIYYP LSTLMLAGMR    50
    DVLVISTPQD TPRFQQLLGD GSQWGMNLQY AVQPSPDGLA QAFIIGEQFI 100
    GNAPSALVLG DNIYYGHDFQ PLLKAADAQS SGATVFAYHV HDPERYGVVQ 150
    FNAQGQAVSI EEKPKAPKSN YAVTGLYFYD QQVVDIAKAV KPSARGELEI 200
    TSVNQAYMQQ GQLNVQTMGR GYAWLDTGTH DSLLDASQFI ATLENRQGLK 250
    VACPEEIAWR SGWINASQLE ALVQPLTKNG YGQYLMQILK ETVF 294
    Length:294
    Mass (Da):32,262
    Last modified:May 1, 2007 - v1
    Checksum:iF889ED40F442F9AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000614 Genomic DNA. Translation: ABO56205.1.
    RefSeqiYP_001121040.1. NC_009256.1.

    Genome annotation databases

    EnsemblBacteriaiABO56205; ABO56205; Bcep1808_3215.
    GeneIDi4954961.
    KEGGibvi:Bcep1808_3215.
    PATRICi19325120. VBIBurVie89221_7502.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000614 Genomic DNA. Translation: ABO56205.1 .
    RefSeqi YP_001121040.1. NC_009256.1.

    3D structure databases

    ProteinModelPortali A4JIV2.
    SMRi A4JIV2. Positions 3-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 269482.Bcep1808_3215.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO56205 ; ABO56205 ; Bcep1808_3215 .
    GeneIDi 4954961.
    KEGGi bvi:Bcep1808_3215.
    PATRICi 19325120. VBIBurVie89221_7502.

    Phylogenomic databases

    eggNOGi COG1209.
    HOGENOMi HOG000283473.
    KOi K00973.
    OMAi FIVGRDF.
    OrthoDBi EOG6RC3RN.

    Enzyme and pathway databases

    BioCyci BVIE269482:GJNA-3288-MONOMER.

    Family and domain databases

    Gene3Di 3.90.550.10. 1 hit.
    InterProi IPR005907. G1P_thy_trans_s.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view ]
    PANTHERi PTHR22572:SF13. PTHR22572:SF13. 1 hit.
    Pfami PF00483. NTP_transferase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53448. SSF53448. 1 hit.
    TIGRFAMsi TIGR01207. rmlA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Burkholderia vietnamiensis G4."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.
      , Hauser L., Kyrpides N., Tiedje J., Richardson P.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: G4 / LMG 22486Imported.

    Entry informationi

    Entry nameiA4JIV2_BURVG
    AccessioniPrimary (citable) accession number: A4JIV2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2007
    Last sequence update: May 1, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3