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Protein

Glucose-1-phosphate thymidylyltransferase

Gene

Bcep1808_3215

Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.UniRule annotation

Catalytic activityi

dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose.UniRule annotation

GO - Molecular functioni

  1. glucose-1-phosphate thymidylyltransferase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. extracellular polysaccharide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-3288-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphate thymidylyltransferaseUniRule annotation (EC:2.7.7.24UniRule annotation)
Gene namesi
Ordered Locus Names:Bcep1808_3215Imported
OrganismiBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))Imported
Taxonomic identifieri269482 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002287 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi269482.Bcep1808_3215.

Structurei

3D structure databases

ProteinModelPortaliA4JIV2.
SMRiA4JIV2. Positions 3-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glucose-1-phosphate thymidylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1209.
HOGENOMiHOG000283473.
KOiK00973.
OMAiEATIFAY.
OrthoDBiEOG6RC3RN.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005907. G1P_thy_trans_s.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR22572:SF13. PTHR22572:SF13. 1 hit.
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01207. rmlA. 1 hit.

Sequencei

Sequence statusi: Complete.

A4JIV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQRKGIILA GGSGTRLHPA TLAISKQLLP VYDKPMIYYP LSTLMLAGMR
60 70 80 90 100
DVLVISTPQD TPRFQQLLGD GSQWGMNLQY AVQPSPDGLA QAFIIGEQFI
110 120 130 140 150
GNAPSALVLG DNIYYGHDFQ PLLKAADAQS SGATVFAYHV HDPERYGVVQ
160 170 180 190 200
FNAQGQAVSI EEKPKAPKSN YAVTGLYFYD QQVVDIAKAV KPSARGELEI
210 220 230 240 250
TSVNQAYMQQ GQLNVQTMGR GYAWLDTGTH DSLLDASQFI ATLENRQGLK
260 270 280 290
VACPEEIAWR SGWINASQLE ALVQPLTKNG YGQYLMQILK ETVF
Length:294
Mass (Da):32,262
Last modified:May 1, 2007 - v1
Checksum:iF889ED40F442F9AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000614 Genomic DNA. Translation: ABO56205.1.
RefSeqiYP_001121040.1. NC_009256.1.

Genome annotation databases

EnsemblBacteriaiABO56205; ABO56205; Bcep1808_3215.
KEGGibvi:Bcep1808_3215.
PATRICi19325120. VBIBurVie89221_7502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000614 Genomic DNA. Translation: ABO56205.1.
RefSeqiYP_001121040.1. NC_009256.1.

3D structure databases

ProteinModelPortaliA4JIV2.
SMRiA4JIV2. Positions 3-294.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269482.Bcep1808_3215.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO56205; ABO56205; Bcep1808_3215.
KEGGibvi:Bcep1808_3215.
PATRICi19325120. VBIBurVie89221_7502.

Phylogenomic databases

eggNOGiCOG1209.
HOGENOMiHOG000283473.
KOiK00973.
OMAiEATIFAY.
OrthoDBiEOG6RC3RN.

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-3288-MONOMER.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005907. G1P_thy_trans_s.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR22572:SF13. PTHR22572:SF13. 1 hit.
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01207. rmlA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: G4 / LMG 22486Imported.

Entry informationi

Entry nameiA4JIV2_BURVG
AccessioniPrimary (citable) accession number: A4JIV2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: April 29, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.