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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei207 – 2071UniRule annotation
Active sitei649 – 6491UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-2580-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Bcep1808_2510
OrganismiBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
Taxonomic identifieri269482 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002287 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 997997Phosphoenolpyruvate carboxylasePRO_1000025553Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269482.Bcep1808_2510.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4JGV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSGSARTA RRNAALPSTD AQTGALATVA NGRAKPATKP KDSIRQTKRT
60 70 80 90 100
TKAAGASKPA ARTREDKDGP LFEDIRFLGR LLGDVVREQE GDTVFDVVET
110 120 130 140 150
IRQTAVKFRR EDDSQAAQTL EKKLRKLTPE QTVSVVRAFS YFSHLANIAE
160 170 180 190 200
DRHHNRRRRI HALAGSAPQP GTVAYALEQL KTSGNASKRV LQRFFDDALI
210 220 230 240 250
VPVLTAHPTE VQRKSILDAQ HDIARLLAER DQPLTARERA YNESMLRARV
260 270 280 290 300
TALWQTRMLR DARLTVGDEI ENALSYYRTT FLDELPALYG DIEAALAEHG
310 320 330 340 350
LPARVPAFFQ MGSWIGGDRD GNPNVTAATL DEAINRQAAV ILEHYLEQVH
360 370 380 390 400
KLGAELSVSN LLVGANDAVK ALAAASPDQS PHRVDEPYRR ALIGIYTRLA
410 420 430 440 450
ASARVRLGEG TVPVRSAGRG APPVRAVPYA DSEAFVADLK VLTASLEEHH
460 470 480 490 500
GASLAAPRLT PLMRAAEVFG FHLSSIDLRQ SSDIHEAVVA ELFARAGVHA
510 520 530 540 550
DYASLSEDDK LIALLAALAD PRPLRSPYIE YSALAQSELG VFEKAREVRA
560 570 580 590 600
QFGPRAVRNY IISHTETVSD LVEVLLLQKE TGLLEGAFGA AHDSARNGLM
610 620 630 640 650
VIPLFETIPD LRDAARIMRE YFALPGIEAL IAHQGAEQEV MLGYSDSNKD
660 670 680 690 700
GGFLTSNWEL YRAELALVDL FRDRKITLRL FHGRGGTVGR GGGPTYQAIL
710 720 730 740 750
SQPPGTVNGQ IRLTEQGEVI ASKFANPEIG RRNLETVVAA TLEASLLPQS
760 770 780 790 800
NAPAQLPAFE AAMQALSDAA MASYRALVYE TPGFTDYFFA ATPITEIAEL
810 820 830 840 850
NIGSRPASRK LQDPKNRRIE DLRAIPWGFS WGQCRLLLTG WYGFGSAVSA
860 870 880 890 900
YLDGAPDAAA RTKRVALLKK MNKTWPFFAN LLSNMDMVLA KTDLAVASRY
910 920 930 940 950
AQLVADRKLR KHVFERIVAE WERTAQALAE ITGHEGRLAT NPLLARSIKN
960 970 980 990
RFPYLDPLNH LQVELIKRHR AGDTNARLRR GIHLTINGIA AGLRNTG
Length:997
Mass (Da):109,405
Last modified:May 1, 2007 - v1
Checksum:iFADFAC9E2115183C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000614 Genomic DNA. Translation: ABO55508.1.
RefSeqiWP_011885700.1. NC_009256.1.
YP_001120343.1. NC_009256.1.

Genome annotation databases

EnsemblBacteriaiABO55508; ABO55508; Bcep1808_2510.
KEGGibvi:Bcep1808_2510.
PATRICi19323634. VBIBurVie89221_6761.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000614 Genomic DNA. Translation: ABO55508.1.
RefSeqiWP_011885700.1. NC_009256.1.
YP_001120343.1. NC_009256.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269482.Bcep1808_2510.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO55508; ABO55508; Bcep1808_2510.
KEGGibvi:Bcep1808_2510.
PATRICi19323634. VBIBurVie89221_6761.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBVIE269482:GJNA-2580-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia vietnamiensis G4."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Tiedje J., Richardson P.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: G4 / LMG 22486.

Entry informationi

Entry nameiCAPP_BURVG
AccessioniPrimary (citable) accession number: A4JGV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 1, 2007
Last modified: April 29, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.