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A4JBU7 (A4JBU7_BURVG) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 1 HAMAP MF_00051
Short name=SHMT 1 HAMAP MF_00051
Short name=Serine methylase 1 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA1 HAMAP MF_00051
Ordered Locus Names:Bcep1808_0738
OrganismBurkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808)) [Complete proteome] [HAMAP]
Taxonomic identifier269482 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2461N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
A4JBU7 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: E8E8FE5EFFCD880A

FASTA43146,596
        10         20         30         40         50         60 
MYSAAPVNLY TLNGNRMFDR AQSTIANVDP EIFAAIEQEN RRQEDHIELI ASENYTSPAV 

        70         80         90        100        110        120 
MAAQGSQLTN KYAEGYPGKR YYGGCEYVDV VEQLAIDRVK QLFGAEAANV QPNSGSQANQ 

       130        140        150        160        170        180 
GVFFAMLKPG DTIMGMSLAH GGHLTHGSPV NMSGKWFNVV SYGLNENEDI DYDAAEKLAQ 

       190        200        210        220        230        240 
EHKPKLIVAG ASAFALKIDF ARMAQIAKSV GAYLMVDMAH YAGLIAAGVY PNPVPHADFV 

       250        260        270        280        290        300 
TTTTHKSLRG PRGGVILMKA EYEKQINSAI FPGIQGGPLM HVIAAKAVAF KEALSPEFKA 

       310        320        330        340        350        360 
YQQKVVENAR VLAETLVKRG LRIVSGRTES HVMLVDLRAK HITGKAAEAA LGAAHITVNK 

       370        380        390        400        410        420 
NAIPNDPEKP FVTSGVRLGS PAMTTRGFGP AEAEQVGNLI ADVLENPEDA ATLERVRAQV 

       430 
AELTKRFPVY R

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia vietnamiensis G4."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Tiedje J., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: G4 / LMG 22486.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000614 Genomic DNA. Translation: ABO53750.1.
RefSeqYP_001118585.1. NC_009256.1.

3D structure databases

ProteinModelPortalA4JBU7.
SMRA4JBU7. Positions 20-430.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4JBU7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4952434.
GenomeReviewsGene locus Bcep1808_0738 in contig CP000614_GR.
KEGGbvi:Bcep1808_0738.
PATRIC19319925. VBIBurVie89221_4952.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMARIDFERI.
ProtClustDBPRK00011.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4JBU7_BURVG
AccessionPrimary (citable) accession number: A4JBU7
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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