Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A4JBA9 (A4JBA9_BURVG) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length202 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP-Rule MF_00376

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP-Rule MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP-Rule MF_00376

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00376.

Sequence similarities

Belongs to the CoaE family. HAMAP-Rule MF_00376

Contains 1 DPCK (dephospho-CoA kinase) domain. HAMAP-Rule MF_00376

Contains DPCK (dephospho-CoA kinase) domain. SAAS SAAS001977

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain3 – 201199DPCK By similarity HAMAP-Rule MF_00376
Nucleotide binding8 – 158ATP By similarity HAMAP-Rule MF_00376
Nucleotide binding11 – 166ADP PDB 4I1V
Nucleotide binding175 – 1806ADP PDB 4I1V
Region11 – 144Sulfate 1 binding
Region80 – 812Sulfate 4 binding
Region117 – 1204Sulfate 5 binding

Sites

Binding site271Sulfate 2
Binding site371Sulfate 2
Binding site441Chloride; via amide nitrogen
Binding site681Sulfate 3
Binding site881Sulfate 5
Binding site921Sulfate 5
Binding site1001Sulfate 6
Binding site1031Sulfate 2; via amide nitrogen
Binding site1261Sulfate 7
Binding site1401ADP PDB 4I1V
Binding site1401Sulfate 8
Binding site1441ADP PDB 4I1V
Binding site1441Sulfate 1
Binding site1761Sulfate 8; via carbonyl oxygen

Sequences

Sequence LengthMass (Da)Tools
A4JBA9 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: EE9E620DAE950D0B

FASTA20221,889
        10         20         30         40         50         60 
MYAIGLTGGI GSGKTTVADL FAARGASLVD TDLIAHRITA PAGLAMPAIE QTFGPAFVAA 

        70         80         90        100        110        120 
DGSLDRARMR ALIFSDEDAR RRLEAITHPL IRAETEREAR DAQGPYVIFV VPLLVESRNW 

       130        140        150        160        170        180 
KARCDRVLVV DCPVDTQIAR VMQRNGFTRE QVEAIIARQA TREARLAAAD DVIVNDAATP 

       190        200 
DALAVQVDAL HQRYLAFAAA KH 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of chromosome 1 of Burkholderia vietnamiensis G4."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Tiedje J., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: G4 / LMG 22486.
[2]"Apo crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis."
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Edwards T.E., Abendroth J.
Submitted (NOV-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) IN COMPLEX WITH CHLORIDE AND SULFATE.
[3]"Crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis bound to ADP."
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Edwards T.E., Clifton M.C., Sankaran B.
Submitted (NOV-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) IN COMPLEX WITH ADP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000614 Genomic DNA. Translation: ABO53562.1.
RefSeqYP_001118397.1. NC_009256.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4I1UX-ray2.05A/B1-202[»]
4I1VX-ray2.60A/B1-202[»]
ProteinModelPortalA4JBA9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269482.Bcep1808_0550.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO53562; ABO53562; Bcep1808_0550.
GeneID4952243.
KEGGbvi:Bcep1808_0550.
PATRIC19319514. VBIBurVie89221_4749.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0237.
HOGENOMHOG000020769.
KOK00859.
OMARERVFNH.
OrthoDBEOG6HTP3H.

Enzyme and pathway databases

BioCycBVIE269482:GJNA-570-MONOMER.
UniPathwayUPA00241; UER00356.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00376. Dephospho_CoA_kinase.
InterProIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00152. TIGR00152. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4JBA9_BURVG
AccessionPrimary (citable) accession number: A4JBA9
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)