Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4J906 (A4J906_DESRM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UvrABC system protein C HAMAP-Rule MF_00203
Short name=Protein UvrC HAMAP-Rule MF_00203
Alternative name(s):
Excinuclease ABC subunit C HAMAP-Rule MF_00203
Gene names
Name:uvrC HAMAP-Rule MF_00203
Ordered Locus Names:Dred_3057
OrganismDesulfotomaculum reducens (strain MI-1) [Complete proteome] [HAMAP] EMBL ABO51559.1
Taxonomic identifier349161 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfotomaculum ›

Protein attributes

Sequence length588 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. HAMAP-Rule MF_00203 SAAS SAAS004791

Subunit structure

Interacts with UvrB in an incision complex By similarity. HAMAP-Rule MF_00203 SAAS SAAS004791

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00203 SAAS SAAS004791.

Sequence similarities

Belongs to the UvrC family. HAMAP-Rule MF_00203

Contains 1 GIY-YIG domain. HAMAP-Rule MF_00203 SAAS SAAS004791

Contains 1 UVR domain. HAMAP-Rule MF_00203 SAAS SAAS004791

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain173 – 20836UVR By similarity HAMAP-Rule MF_00203

Sequences

Sequence LengthMass (Da)Tools
A4J906 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: D6315F62C67DAECE

FASTA58867,830
        10         20         30         40         50         60 
MGKAVSLKNR VRSYFQAGAK QAPKVKAMLG RAVDLDFIVT DSEMEALILE NNLIKEHRPK 

        70         80         90        100        110        120 
YNILLKDDKT YPYIKVTVQE EFPRVYLTRR VLKDRARYFG PFTNVGAVNE TMRLLKKIFP 

       130        140        150        160        170        180 
LRTCKQRKLS PRDRPCLNYH IKRCLGPCCN LVERQTYRET VNEVVLFLEG RQEDLMKRLR 

       190        200        210        220        230        240 
QRMEEAAEKL EFEKAAELRD QLLAVEKIVE RQKVVSTDLV DQDVIAMARG FDESCLTVFF 

       250        260        270        280        290        300 
IRGGKLIGRE HYFLEGTDTL ERGEIMTTFI QQFYNQTEFI PAEVLISEEI AKPELLRSWL 

       310        320        330        340        350        360 
SELRGSKVTI KAPKRGDKHK LVEMAAQNAL LSLEQAKLQR QANREAVDGA LAELMAALGL 

       370        380        390        400        410        420 
ENPPHRMECY DISNIQGTET VSSMVVFEEG RPKKDQYRRF KIRWVEGPND FASMHETLTR 

       430        440        450        460        470        480 
RFSRAKEEQD LLSRGELTPK QAKFTRLPDL IIIDGGKGQL SAARQAMLEQ GFAHIATFGL 

       490        500        510        520        530        540 
AKEEELLFAP GRPDPIRLPR ESKGLQMLQR LRDEAHRFAV TYHRKLRTKR NLKSLLDEID 

       550        560        570        580 
GIGAVRRREL YKAYKNLESI KQASVEELAK IPGMNTKAAE AVYNYFRE

« Hide

References

[1]"Complete sequence of Desulfotomaculum reducens MI-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Tebo B.M., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MI-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000612 Genomic DNA. Translation: ABO51559.1.
RefSeqYP_001114384.1. NC_009253.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING349161.Dred_3057.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO51559; ABO51559; Dred_3057.
GeneID4956755.
KEGGdrm:Dred_3057.
PATRIC21732619. VBIDesRed82656_3345.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0322.
HOGENOMHOG000279960.
KOK03703.
OMAQKLFPIR.
ProtClustDBPRK00558.

Enzyme and pathway databases

BioCycDRED349161:GHP6-3151-MONOMER.

Family and domain databases

Gene3D4.10.860.10. 1 hit.
HAMAPMF_00203. UvrC.
InterProIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamPF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF47781. RuvA_2_like. 1 hit.
SSF46600. UvrB_C. 1 hit.
SSF82771. UvrC_N. 1 hit.
TIGRFAMsTIGR00194. uvrC. 1 hit.
PROSITEPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4J906_DESRM
AccessionPrimary (citable) accession number: A4J906
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info