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A4J7X3 (A4J7X3_DESRM) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thioredoxin reductase RuleBase RU003881

EC=1.8.1.9 RuleBase RU003881
Gene names
Ordered Locus Names:Dred_2670 EMBL ABO51176.1
OrganismDesulfotomaculum reducens (strain MI-1) [Complete proteome] [HAMAP] EMBL ABO51176.1
Taxonomic identifier349161 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfotomaculum

Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881

Cofactor

Binds 1 FAD per subunit By similarity. RuleBase RU003881

Sequence similarities

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

Sequences

Sequence LengthMass (Da)Tools
A4J7X3 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: AF823B4A4CD4660A

FASTA41044,690
        10         20         30         40         50         60 
MSNTTHDIII IGAGPAGLAA GIYGARAKLR TLIIEKGAIG GMASNTREIV NYPGFKQTSG 

        70         80         90        100        110        120 
TALTKEMAEH AKEMGTEIIK GEVKTVDLSG EIKRVVTRKK QEFTARAVIL ATGTLPRVLG 

       130        140        150        160        170        180 
IPGEKELRGN GVAYCATCDA EFFEGQHVVV VGSGDQAIEE GMFIAKFANQ VTVIVLHDEG 

       190        200        210        220        230        240 
KLDCNRLSAE KALHHPKLKF VWNSTLTAVQ GDEEVTGVQV KNIKTGEMSE IPCQGVFFFV 

       250        260        270        280        290        300 
GMIPATHFLK GQVELDDRGY VMVNDLLETS VEGVFAAGDL RPKYLRQVVT ATADGAAAVV 

       310        320        330        340        350        360 
AAERYLQEKE NLRTTVLEAE KPVILAFWSP EDQASLQAVS RVEKVVSELP NEYLFVKTDV 

       370        380        390        400        410 
TRQRMLAKKY QVTTLPRVFV LNKGEVVQTI DTDAEVDDIK EILKALIQQA 

« Hide

References

[1]"Complete sequence of Desulfotomaculum reducens MI-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Tebo B.M., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MI-1 EMBL ABO51176.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000612 Genomic DNA. Translation: ABO51176.1.
RefSeqYP_001114001.1. NC_009253.1.

3D structure databases

ProteinModelPortalA4J7X3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349161.Dred_2670.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO51176; ABO51176; Dred_2670.
GeneID4958660.
KEGGdrm:Dred_2670.
PATRIC21731753. VBIDesRed82656_2923.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHOG000072911.
KOK00384.
OMAVLDQGKE.
OrthoDBEOG65XN2W.

Enzyme and pathway databases

BioCycDRED349161:GHP6-2749-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR008255. Pyr_nucl-diS_OxRdtase_2_AS.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
IPR005982. Thioredox_Rdtase.
IPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
PF00085. Thioredoxin. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
SUPFAMSSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR01292. TRX_reduct. 1 hit.
PROSITEPS00573. PYRIDINE_REDOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4J7X3_DESRM
AccessionPrimary (citable) accession number: A4J7X3
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)