A4IWK8 (A4IWK8_FRATW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Signal peptidase I EMBL ABO46310.1
EC=3.4.21.89 EMBL ABO46310.1

Gene names

Name:	lepB EMBL ABO46310.1
Ordered Locus Names:	FTW_0371

Organism

Francisella tularensis subsp. tularensis (strain WY96-3418) [Complete proteome] [HAMAP]

Taxonomic identifier

418136 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Molecular function	Hydrolase EMBL ABO46310.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4IWK8 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: CC257F0B336EADC5	FASTA	287	32,836
	10 20 30 40 50 60 MEILNYILNL GFTFWLLFLT IASGLIYIID FVFFQKSRLA AYTDELKGLS KKQKRQFYKD 70 80 90 100 110 120 RGLKAPFIAD QARSLFSVFF VVFLLRTFLI GNFLIPTASM TPTLPVGDFI FVNKTAYGIR 130 140 150 160 170 180 APFTNETLIK VGEPKRGDIV VFHFPVNPNV DFVKRVIGLP GDVISYKDKM LTINGKKLEY 190 200 210 220 230 240 TNCNRDAMNY YNQSLAAGSG DTVCTENLDG VKHEVDWIES IKGTDFENLK VPAGQYFVMG 250 260 270 280 DNRDNSEDSR YWGFVPDKDL VGKAKVVWMS WDKIDKKVRW DEIGKVF

References

[1]

"Complete genomic characterization of a pathogenic A.II strain of Francisella tularensis subspecies tularensis." Beckstrom-Sternberg S.M., Auerbach R.K., Godbole S., Pearson J.V., Beckstrom-Sternberg J.S., Deng Z., Munk C., Kubota K., Zhou Y., Bruce D., Noronha J., Scheuermann R.H., Wang A., Wei X., Wang J., Hao J., Wagner D.M., Brettin T.S. , Brown N., Gilna P., Keim P.S. PLoS ONE 2:E947-E947(2007) [PubMed: 17895988] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000608 Genomic DNA. Translation: ABO46310.1.
RefSeq	YP_001121430.1. NC_009257.1.
3D structure databases
ProteinModelPortal	A4IWK8.
ModBase	Search...
Protein-protein interaction databases
STRING	A4IWK8.
Protein family/group databases
MEROPS	S26.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4960459.
GenomeReviews	Gene locus FTW_0371 in contig CP000608_GR.
KEGG	ftw:FTW_0371.
PATRIC	17968066. VBIFraTul58433_0376.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0681.
HOGENOM	HBG596607.
OMA	RYPSDPN.
ProtClustDB	CLSK935083.
Family and domain databases
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019758. Pept_S26A_signal_pept_1_CS. IPR019757. Pept_S26A_signal_pept_1_Lys-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. IPR019533. Peptidase_S26. IPR019766. Peptidase_S26A_all-beta_subdom. [Graphical view]
Gene3D	G3DSA:2.10.109.10. Pept_S24_S26_C. 2 hits. G3DSA:2.170.230.10. Peptidase_S26A_all-beta_subdom. 1 hit.
KO	K03100.
Pfam	PF00717. Peptidase_S24. 1 hit. PF10502. Peptidase_S26. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. Sigpep_I_bact. 1 hit.
PROSITE	PS00760. SPASE_I_2. 1 hit. PS00761. SPASE_I_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4IWK8_FRATW

Accession

Primary (citable) accession number: A4IWK8

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)