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A4ISE6 (FENR_GEOTN) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:GTNG_2905
OrganismGeobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]
Taxonomic identifier420246 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 332332Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364841

Sites

Binding site201FAD By similarity
Binding site391FAD By similarity
Binding site471FAD By similarity
Binding site521FAD By similarity
Binding site921FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1261FAD; via amide nitrogen By similarity
Binding site2881FAD By similarity
Binding site3291FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A4ISE6 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 1AE055A2AF7BB92B

FASTA33236,667
        10         20         30         40         50         60 
MSVREDRNVY DVTVIGGGPT GMFAAFYGGL RQMNVKIIES LPQLGGQLAA LYPEKYIYDI 

        70         80         90        100        110        120 
AGFPKVRAQE LVDQLKEQLS RFSPTICLNQ SVEMLEKQED GTFKLTTDKE IHYSKTVIIT 

       130        140        150        160        170        180 
AGNGAFQPRR LEIDSASQYE GKNLHYFISD LQQFAGKRVL VCGGGDSAVD WSLMLEPIAA 

       190        200        210        220        230        240 
SVTIVHRRDK FRAHEHSVEQ LMNSRVQVKT PYVPAELIGD EQGIRQVVLE HVKEGAKETI 

       250        260        270        280        290        300 
DVDAVIVNYG FISSLGPIKN WGLDIEKNSI KVNSRMETNI PGVYAAGDIC TYDGKIKLIA 

       310        320        330 
CGFGEAPIAI SSAKTYIDPT ARMQPAHSSS LF

« Hide

References

[1]"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir."
Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.
Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NG80-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000557 Genomic DNA. Translation: ABO68250.1.
RefSeqYP_001126995.1. NC_009328.1.

3D structure databases

ProteinModelPortalA4ISE6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4ISE6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4967831.
GenomeReviewsGene locus GTNG_2905 in contig CP000557_GR.
KEGGgtn:GTNG_2905.
NMPDRfig|420246.5.peg.2785.
PATRIC21982431. VBIGeoThe136879_3059.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK2459135.

Enzyme and pathway databases

BioCycGTHE420246:GTNG_2905-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_GEOTN
AccessionPrimary (citable) accession number: A4ISE6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 1, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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