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A4ISB8 (G6PI_GEOTN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:GTNG_2877
OrganismGeobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]
Taxonomic identifier420246 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 449449Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013970

Sites

Active site2901Proton donor By similarity
Active site3111 By similarity
Active site4251 By similarity

Amino acid modifications

Modified residue381Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
A4ISB8 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 398C72538FC46485

FASTA44950,585
        10         20         30         40         50         60 
MTHIRFDYSK ALAFFGEHEL TYLRDAVKVA HHSLHEKTGV GNDFLGWLDW PVNYDKEEFA 

        70         80         90        100        110        120 
RIKQAAKKIQ SDSDVLLVIG IGGSYLGARA AIEMLHHSFY NALPKEKRST PQIIFVGNNI 

       130        140        150        160        170        180 
SSTYMKDVID FLEGKDFSIN VISKSGTTTE PAIAFRIFRK LLEDKYGKEE ARRRIYATTD 

       190        200        210        220        230        240 
RARGALRTLA DEEGYETFVI PDDIGGRYSV LTAVGLLPIA ASGADIDAMM EGAAKAREDF 

       250        260        270        280        290        300 
SRSELEENAA YQYAAIRNIL YNKGKTIELL VNYEPALHYF AEWWKQLFGE SEGKDQKGIY 

       310        320        330        340        350        360 
PASADFSTDL HSLGQYIQEG RRDLFETVLK LEEPRHELVI EAEESDLDGL NYLAGQTVDF 

       370        380        390        400        410        420 
VNTKAFEGTL LAHTDGGVPN LVVTLPKLDE YTFGYLVYFF EKACAMSGYL LGVNPFDQPG 

       430        440 
VEAYKKNMFA LLGKPGYEEL KDELEKRLK 

« Hide

References

[1]"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir."
Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.
Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NG80-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000557 Genomic DNA. Translation: ABO68222.1.
RefSeqYP_001126967.1. NC_009328.1.

3D structure databases

ProteinModelPortalA4ISB8.
SMRA4ISB8. Positions 4-448.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING420246.GTNG_2877.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO68222; ABO68222; GTNG_2877.
GeneID4967803.
KEGGgtn:GTNG_2877.
PATRIC21982361. VBIGeoThe136879_3024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAQVIFIGN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycGTHE420246:GIXT-2972-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_GEOTN
AccessionPrimary (citable) accession number: A4ISB8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 1, 2007
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways