A4IQK9 (A4IQK9_GEOTN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	zwf EMBL ABO67613.1
Ordered Locus Names:	GTNG_2264

Organism

Geobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]

Taxonomic identifier

420246 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	479 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4IQK9 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 66F0776BCA662F2E	FASTA	479	55,401
	10 20 30 40 50 60 MAKRKLFPSL YRLYEKGHLN ERFAVVGVAR RPLSADEFRH YVRDSVETAL NQELTDGNFI 70 80 90 100 110 120 SHFYYHPFDV TEAESYQRLK ALLEQLDETY QTEGNCIFYL AMAPEFFGTV TSRLQSERLT 130 140 150 160 170 180 DTRGFKRLVI EKPFGHDLVS AQKLNEEIRR VFSEREIYRI DHYLGKEMVQ NIEVIRFSNA 190 200 210 220 230 240 IFEPLWNNRF ISNIQITSSE TLGVEDRGRY YDHSGALRDM VQNHMLQMVA LLAMEPPIKL 250 260 270 280 290 300 TTDDIRHEKV KVLRALRPVA HDEVDQYFVR GQYGRGVIRG QAVPAYREEP NVDPNSNTET 310 320 330 340 350 360 FVAGKLMIDN FRWAGVPFYI RTGKRMAEKS TKIVVQFKDV PMNLYYRTNE TIAPNLLVIH 370 380 390 400 410 420 IQPDEGITLH LNGKKTGESS TITAPFKLDY CNNCIDGINT PEAYEKLLYD CMRGDATNFT 430 440 450 460 470 HWDEVAASWQ FVDPISDVWA NTKADDFPNY EAGSMGPAAA DELLRKDGFH WWPIEHPKP

References

[1]

"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir." Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L. Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000557 Genomic DNA. Translation: ABO67613.1.
RefSeq	YP_001126358.1. NC_009328.1.
3D structure databases
ProteinModelPortal	A4IQK9.
ModBase	Search...
Protein-protein interaction databases
STRING	A4IQK9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4967191.
GenomeReviews	Gene locus GTNG_2264 in contig CP000557_GR.
KEGG	gtn:GTNG_2264.
NMPDR	fig|420246.5.peg.2172.
PATRIC	21981053. VBIGeoThe136879_2388.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
HOGENOM	HBG322449.
OMA	DEVAASW.
PhylomeDB	A4IQK9.
ProtClustDB	PRK05722.
Family and domain databases
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00036.
PANTHER	PTHR23429. G6PDH. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. Zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4IQK9_GEOTN

Accession

Primary (citable) accession number: A4IQK9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)