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A4IQ83

- TRPF_GEOTN

UniProt

A4IQ83 - TRPF_GEOTN

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Geobacillus thermodenitrificans (strain NG80-2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciGTHE420246:GIXT-2214-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:GTNG_2135
OrganismiGeobacillus thermodenitrificans (strain NG80-2)
Taxonomic identifieri420246 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
ProteomesiUP000001578: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000018595Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi420246.GTNG_2135.

Structurei

3D structure databases

ProteinModelPortaliA4IQ83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A4IQ83-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAMVRLKYCG NRSADDVQVA LASGADYLGF IFTESKRNVS PEEVKHWLAL
60 70 80 90 100
ASLGDKQLVG VFVNASVDQI ASVTEQLPLH VVQCHGHETP AELAVVKEAT
110 120 130 140 150
RLSVWKAIHH DDGALETMKQ YAGVADGYVV DSRVAGAWGG TGVSFDWEAV
160 170 180 190 200
PRYLEEAARQ GVPCFIAGGI TPDNIERLLA YRPDGIDISS GIETDGRKDP
210 220
AKMKQIEEKT KQYLAVGKGA K
Length:221
Mass (Da):23,927
Last modified:May 1, 2007 - v1
Checksum:i254CC279D6784367
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000557 Genomic DNA. Translation: ABO67487.1.
RefSeqiWP_011887693.1. NC_009328.1.
YP_001126232.1. NC_009328.1.

Genome annotation databases

EnsemblBacteriaiABO67487; ABO67487; GTNG_2135.
GeneIDi4967063.
KEGGigtn:GTNG_2135.
PATRICi21980775. VBIGeoThe136879_2249.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000557 Genomic DNA. Translation: ABO67487.1 .
RefSeqi WP_011887693.1. NC_009328.1.
YP_001126232.1. NC_009328.1.

3D structure databases

ProteinModelPortali A4IQ83.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 420246.GTNG_2135.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO67487 ; ABO67487 ; GTNG_2135 .
GeneIDi 4967063.
KEGGi gtn:GTNG_2135.
PATRICi 21980775. VBIGeoThe136879_2249.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci GTHE420246:GIXT-2214-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir."
    Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.
    Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NG80-2.

Entry informationi

Entry nameiTRPF_GEOTN
AccessioniPrimary (citable) accession number: A4IQ83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 1, 2007
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3