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Protein
Submitted name:

DNA topoisomerase III

Gene

GTNG_1531

Organism
Geobacillus thermodenitrificans (strain NG80-2)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseImported

Enzyme and pathway databases

BioCyciGTHE420246:GIXT-1597-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA topoisomerase IIIImported
Gene namesi
Ordered Locus Names:GTNG_1531Imported
OrganismiGeobacillus thermodenitrificans (strain NG80-2)Imported
Taxonomic identifieri420246 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001578 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi420246.GTNG_1531.

Structurei

3D structure databases

ProteinModelPortaliA4INJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 135ToprimInterPro annotationAdd BLAST134

Phylogenomic databases

eggNOGiENOG4108IYH. Bacteria.
COG0550. LUCA.
HOGENOMiHOG000086847.
KOiK03169.
OMAiFCPDAEY.
OrthoDBiPOG091H028X.

Family and domain databases

CDDicd00186. TOP1Ac. 1 hit.
cd03362. TOPRIM_TopoIA_TopoIII. 1 hit.
Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 1 hit.
3.40.50.140. 1 hit.
InterProiView protein in InterPro
IPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR023406. Topo_IA_AS.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR013498. Topo_IA_Znf.
IPR005738. TopoIII.
IPR006171. TOPRIM_domain.
IPR034144. TOPRIM_TopoIII.
PANTHERiPTHR11390. PTHR11390. 1 hit.
PfamiView protein in Pfam
PF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
PF01396. zf-C4_Topoisom. 2 hits.
PRINTSiPR00417. PRTPISMRASEI.
SMARTiView protein in SMART
SM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
SUPFAMiSSF56712. SSF56712. 1 hit.
TIGRFAMsiTIGR01056. topB. 1 hit.
PROSITEiView protein in PROSITE
PS00396. TOPOISOMERASE_I_PROK. 1 hit.
PS50880. TOPRIM. 1 hit.

Sequencei

Sequence statusi: Complete.

A4INJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSLVLAEKP SVARDIARVL GCKKTHKSYL EGPRYIVTWA LGHLVELKMP
60 70 80 90 100
EDYDRKYETW RLEDLPIIPK KMGLKVIRQT SHQFRAIERL AKRRDVKDCI
110 120 130 140 150
IATDAGREGE LVARWILQKI DWKKPIWRLW ISSQTDQAIR DGFRQLKPGT
160 170 180 190 200
QFDRLYESAI CRAEADWLIG LNVTRALTTK YNDPLSAGRV QTPTLAMIIE
210 220 230 240 250
REREIQSFVP VPYWTIHARI GSVTAVWERH GGKRLFDKDE ANELMTRLKG
260 270 280 290 300
QPARVTSVKR KRKSEPVPLP YDLTELQREA NKRFGFSAKK TLSVLQRLYE
310 320 330 340 350
QHKLVTYPRT DSRYLPSDMK ATMTDRLLAM KPGYEDVISS LLTKKNVKAA
360 370 380 390 400
NRVFQDDKVT DHHAIIPTDE RLDLAKLSVD ERKLYDMIAR RFLALFYPPY
410 420 430 440 450
EYETATVVFE IGDETFVARE TAVVNAGFKA VLGKEETEAK PTLLHLSEGQ
460 470 480 490 500
TLASVQLEME QSFTEPPSRY SEADLLAQME RYGLGTPATR ADIIERLVET
510 520 530 540 550
EVVERKDGRF YPTKKGKQLI ELVNEELKSP ELTARWEREL EAIARGKGNP
560 570 580 590 600
KQFLANIRRQ TEQLVTEIKQ SEQTYKAPNL TNLTCPECGS LLKERKTKDG
610 620 630 640 650
RMLVCSNLEC RYRRRRDPKL SNRRCPQCHR RMEMHEGKAG LYFQCRPCNI
660 670 680 690
VEKAEETKRT SAKGTERALL KKYSPSNESF GTSLGELLKQ ALEKKE
Length:696
Mass (Da):80,353
Last modified:May 1, 2007 - v1
Checksum:i8B31B7B70FE03F85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000557 Genomic DNA. Translation: ABO66901.1.
RefSeqiWP_008879173.1. NC_009328.1.

Genome annotation databases

EnsemblBacteriaiABO66901; ABO66901; GTNG_1531.
KEGGigtn:GTNG_1531.
PATRICi21979491. VBIGeoThe136879_1623.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000557 Genomic DNA. Translation: ABO66901.1.
RefSeqiWP_008879173.1. NC_009328.1.

3D structure databases

ProteinModelPortaliA4INJ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi420246.GTNG_1531.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO66901; ABO66901; GTNG_1531.
KEGGigtn:GTNG_1531.
PATRICi21979491. VBIGeoThe136879_1623.

Phylogenomic databases

eggNOGiENOG4108IYH. Bacteria.
COG0550. LUCA.
HOGENOMiHOG000086847.
KOiK03169.
OMAiFCPDAEY.
OrthoDBiPOG091H028X.

Enzyme and pathway databases

BioCyciGTHE420246:GIXT-1597-MONOMER.

Family and domain databases

CDDicd00186. TOP1Ac. 1 hit.
cd03362. TOPRIM_TopoIA_TopoIII. 1 hit.
Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 1 hit.
3.40.50.140. 1 hit.
InterProiView protein in InterPro
IPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR023406. Topo_IA_AS.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR013498. Topo_IA_Znf.
IPR005738. TopoIII.
IPR006171. TOPRIM_domain.
IPR034144. TOPRIM_TopoIII.
PANTHERiPTHR11390. PTHR11390. 1 hit.
PfamiView protein in Pfam
PF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
PF01396. zf-C4_Topoisom. 2 hits.
PRINTSiPR00417. PRTPISMRASEI.
SMARTiView protein in SMART
SM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
SUPFAMiSSF56712. SSF56712. 1 hit.
TIGRFAMsiTIGR01056. topB. 1 hit.
PROSITEiView protein in PROSITE
PS00396. TOPOISOMERASE_I_PROK. 1 hit.
PS50880. TOPRIM. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA4INJ7_GEOTN
AccessioniPrimary (citable) accession number: A4INJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: April 12, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.