Reviewed, UniProtKB/Swiss-Prot A4IMR6 (MQO_GEOTN)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	GTNG_1250

Organism

Geobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]

Taxonomic identifier

420246 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	Probable malate:quinone oxidoreductase		PRO_1000023802

Sequences

	Sequence		Length	Mass (Da)
	A4IMR6-1 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 4618C316745A7349	FASTA	501	55,566
	10 20 30 40 50 60 MGNKQTKTDV ILIGAGIMSA TLGTLLKELA PEWDITVFER LEEAGVESSN EWNNAGTGHA 70 80 90 100 110 120 ALCELNYTVE KPDGSIDISK AIKINEQFYV SLQFWAYLVN SGVLRDPKEF IRPLPHMSFV 130 140 150 160 170 180 QGEDNVAFLK KRYETMVNNP LFKGMEFSDD PKKLAEWIPL MMENRVVNEP IAATRIESGT 190 200 210 220 230 240 DVNFGALTRK LFEHLKRKNV EIHYRHHVDD IKRTSDGLWE LKVRDLDSGA VERHVAKFVF 250 260 270 280 290 300 IGAGGGSLHL LQKSGIPEGR GIGGFPVSGL FMVCNNPDVV EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRFINN QKMLLFGPFA GFSPKFLKNG SMLDLFTSVK PHNLLTMLAA GVKNMALTNY 370 380 390 400 410 420 LIQQVMLSKE QRMEELREFV PTAKSEEWDV IVAGQRVQVI KDTEAGGKGT LQFGTEVVHA 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVH VMLEVITKCF PERMKEWEPK VREMIPSYGV SLMKNERLLH 490 500 DVQAATAEML GLREGLALQL V

References

[1]

"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir." Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L. Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000557 Genomic DNA. Translation: ABO66620.1.
RefSeq	YP_001125365.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4966189.
GenomeReviews	Gene locus GTNG_1250 in contig CP000557_GR.
KEGG	gtn:GTNG_1250.
NMPDR	fig|420246.5.peg.1212.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_GEOTN

Accession

Primary (citable) accession number: A4IMR6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 1, 2007
Last modified:	November 4, 2008
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)