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A4IMN4 (A4IMN4_GEOTN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186 EMBL ABO66588.1
Ordered Locus Names:GTNG_1216
OrganismGeobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]
Taxonomic identifier420246 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length499 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding413 – 4175ATP By similarity HAMAP MF_00186

Sites

Binding site151Substrate By similarity HAMAP MF_00186
Binding site191ATP By similarity HAMAP MF_00186
Binding site851Substrate By similarity HAMAP MF_00186
Binding site1371Substrate By similarity HAMAP MF_00186
Binding site2471Substrate By similarity HAMAP MF_00186
Binding site2691ATP By similarity HAMAP MF_00186
Binding site3121ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
A4IMN4 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 0F958CDD7D00717C

FASTA49955,118
        10         20         30         40         50         60 
MFMTDQYILA IDQGTTSSRA ILFNRGGEIV HMAQKEFTQY FPQPGWVEHN ANEIWGSVLA 

        70         80         90        100        110        120 
VIASVLSEAQ VKPEQVAAIG ITNQRETTVV WEKESGNPIY NAIVWQSRQT ADICDELKAK 

       130        140        150        160        170        180 
GYDPLFREKT GLLIDAYFSG TKVKWILDHV DGARERAERG ELLFGTIDTW LIWKLSGGRA 

       190        200        210        220        230        240 
HVTDYSNASR TLMFNIHTLE WDDELLAILN VPKAMLPEVR PSSEVYAKTV PHHFFGVEVP 

       250        260        270        280        290        300 
IAGAAGDQQA ALFGQACFAE GMAKNTYGTG CFMLMNTGEK AVQSKHGLLT TIAWGIDGKV 

       310        320        330        340        350        360 
EYALEGSIFV AGSAIQWLRD GLRMIKTAAD SETYAEKVES TDGVYVVPAF VGLGTPYWDS 

       370        380        390        400        410        420 
EVRGAVFGLT RGTTKEHFIR ATLESLAYQT KDVLAAMEAD AGLPLTTLRV DGGAVKNNLL 

       430        440        450        460        470        480 
MQFQSDLLAV PVERPMISET TALGAAYLAG LAVGYWGSRE DIAAQWQLEH RFEPQMTDDK 

       490 
RTALYEGWKK AVRAAMMFK

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References

[1]"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir."
Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.
Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000557 Genomic DNA. Translation: ABO66588.1.
RefSeqYP_001125333.1. NC_009328.1.

3D structure databases

ProteinModelPortalA4IMN4.
SMRA4IMN4. Positions 7-492.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4IMN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4966156.
GenomeReviewsGene locus GTNG_1216 in contig CP000557_GR.
KEGGgtn:GTNG_1216.
NMPDRfig|420246.5.peg.1187.
PATRIC21978793. VBIGeoThe136879_1280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMAALYGQLC.
PhylomeDBA4IMN4.
ProtClustDBPRK00047.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4IMN4_GEOTN
AccessionPrimary (citable) accession number: A4IMN4
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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