ID   A4IKE6_GEOTN            Unreviewed;       428 AA.
AC   A4IKE6;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   RecName: Full=Type VII secretion protein EssB {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=GTNG_0418 {ECO:0000313|EMBL:ABO65800.1};
OS   Geobacillus thermodenitrificans (strain NG80-2).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=420246 {ECO:0000313|EMBL:ABO65800.1, ECO:0000313|Proteomes:UP000001578};
RN   [1] {ECO:0000313|EMBL:ABO65800.1, ECO:0000313|Proteomes:UP000001578}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NG80-2 {ECO:0000313|EMBL:ABO65800.1,
RC   ECO:0000313|Proteomes:UP000001578};
RX   PubMed=17372208; DOI=10.1073/pnas.0609650104;
RA   Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X.,
RA   Han W., Peng X., Liu R., Wang L.;
RT   "Genome and proteome of long-chain alkane degrading Geobacillus
RT   thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
RN   [2] {ECO:0007829|PDB:2YNQ, ECO:0007829|PDB:4ANO}
RP   X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-216.
RX   PubMed=23499020; DOI=10.1016/J.STR.2013.02.007;
RA   Zoltner M., Norman D.G., Fyfe P.K., El Mkami H., Palmer T., Hunter W.N.;
RT   "The architecture of EssB, an integral membrane component of the type VII
RT   secretion system.";
RL   Structure 21:595-603(2013).
CC   -!- INTERACTION:
CC       A4IKE6; A4IKE6: GTNG_0418; NbExp=9; IntAct=EBI-16040818, EBI-16040818;
CC   -!- SIMILARITY: Belongs to the EssB family.
CC       {ECO:0000256|ARBA:ARBA00010163}.
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DR   EMBL; CP000557; ABO65800.1; -; Genomic_DNA.
DR   RefSeq; WP_011886772.1; NC_009328.1.
DR   PDB; 2YNQ; X-ray; 2.40 A; A/B/C/D=241-397.
DR   PDB; 4ANO; X-ray; 1.70 A; A=2-216.
DR   PDBsum; 2YNQ; -.
DR   PDBsum; 4ANO; -.
DR   AlphaFoldDB; A4IKE6; -.
DR   SMR; A4IKE6; -.
DR   DIP; DIP-60143N; -.
DR   KEGG; gtn:GTNG_0418; -.
DR   eggNOG; COG4499; Bacteria.
DR   HOGENOM; CLU_049737_1_1_9; -.
DR   Proteomes; UP000001578; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   Gene3D; 1.25.40.680; Type VII secretion system EssB, C-terminal-like domain; 1.
DR   InterPro; IPR018778; T7SS_EssB.
DR   InterPro; IPR042565; T7SS_EssB_C.
DR   NCBIfam; TIGR03926; T7_EssB; 1.
DR   Pfam; PF10140; YukC; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:2YNQ, ECO:0007829|PDB:4ANO};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        218..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          356..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..389
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        391..428
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   428 AA;  49990 MW;  DD840D6A957054D0 CRC64;
     MSEKKTYLET QLDAVMINDQ PYTVIFQRAK LKMQDPLELE VLKEVDPCIV RDIDVSEDEV
     KVVIKPPSSF LTFAAIRKTT LLSRIRAAIH LVSKVKHHSA RRLIFIVCPE NLMFNRALEP
     FFLHVGVKES LPPDEWDDER LLREVKATVL ALTEGEYRFD EYLKFHETLK CSPIAKELWQ
     ADHLDAVLAV LEKWVDEEEA KERAKVHIPK KRWNMQRYIF FSVIGLLIPA IIYVFYSFFF
     AQPKQEAYIQ STELFLQNKY SDVITTLEDY APEDMPYVIQ YELASSYVMT ESLTEEQRQT
     VSNNITLKTD EQYMLYWIYI GRSQSEEALE LARTIEDRDL IVYALLKYRE QIKGDTDLSG
     DEKQKKLDEI DQEIKEYERE RKESEAQLEE EQQSEQQPPA STPAADSSSE TTQSSHEPSV
     TNNQKSQK
//